Publications by authors named "Pia M Suckrau"
Front Cell Dev Biol
November 2022
Article Synopsis
- - In mammalian cells, membrane traffic pathways connect the compartments of the endomembrane system, with transport between the ER and Golgi using specific cytoplasmic coat protein complexes for cargo identification and carrier formation.
- - The retrograde pathway recycles molecules from the Golgi back to the ER, primarily via the COPI coat complex and a lesser-known pathway regulated by the small GTPase Rab6.
- - A systematic RNA interference screen identified three key proteins (VAMP4, STX5, and SCFD1/SLY1) that are essential for the fusion of Rab6 carriers at the ER, with SCFD1/SLY1 specifically shown to play a crucial role in membrane fusion events.
