The beneficial effects of the herbal medicine Di-Huang-Yin-Zi on patients with traumatic cauda equina injury: A randomized, double-blind, placebo-controlled study.

Objective: This study aimed to investigate the safety and efficacy of Di-Huang-Yin-Zi (DHYZ), also known as Rehmanniae Yin-Zi, a traditional Chinese medicinal formula used for treating of neurological disorders in patients with traumatic cauda equina injury (TCEI).

Methods: In this double-blind, placebo-controlled study, TCEI patients with American Spinal Injury Association (ASIA) impairment grades C were randomized to receive either DHYZ (n = 30) or placebo (n = 30) for 8 weeks. Both groups also received rehabilitation therapy and oral mecobalamine therapy during the treatment.