Acute and Subchronic Toxicity Assessment of Conventional Soxhlet Leaves Extracts in Sprague-Dawley Rats.

Background: In Ghana, leaves together with guava, pawpaw, and lime are processed into a decoction to treat fever. To encourage its usage, preclinical validation of the safety profile of the plant is required. The acute and subchronic toxicities of the conventional Soxhlet ethanolic leaves extract in Sprague-Dawley rats were investigated.