Publications by authors named "Phyllis Ira Spuls"
Background: Many patients with moderate-to-severe atopic dermatitis (AD) require systemic immunomodulating treatment to achieve adequate disease control.
Objective: We sought to systematically evaluate the efficacy and safety of systemic treatments for moderate-to-severe AD.
Methods: A systematic literature search was performed in MEDLINE, EMBASE, and CENTRAL (until June 2012).
Background: Patients with severe atopic eczema frequently require systemic treatment to control their disease. Methotrexate and azathioprine are proposed as off-label treatment options, but direct comparisons are lacking.
Objectives: We sought to compare the efficacy and safety of methotrexate versus azathioprine in adults with severe atopic eczema.