Health status, psychological symptoms, mood, and cognition in L-thyroxine-treated hypothyroid subjects.

Objective: Many hypothyroid subjects receiving L-thyroxine (L-T4) complain of psychological symptoms or cognitive dysfunction. However, there is limited validated information on these self-reports.

Design: Cross-sectional comparison of 20 euthyroid and 34 treated hypothyroid subjects, aged 20-45 years, with normal thyroid-stimulating hormone (TSH) levels.

Hot flashes and estrogen therapy do not influence cognition in early menopausal women.

Objective: To examine how menopausal symptoms and estrogen therapy (ET)-induced symptom relief affect cognition in early menopause.

Design: There were two components. Part 1 was a cross-sectional study of 37 healthy, recently postmenopausal women with diverse menopausal symptoms.