Effect of age on the median effective dose and 95% effective dose of intravenous fentanyl for blunting the hemodynamic response to tracheal intubation: A double-blind, up-and-down sequential method trial.

Background And Aims: Control of the hemodynamic response during intubation is essential. To assess the effect of age on the median effective dose (ED50) and 95% effective dose (ED95) of fentanyl for blunting the hemodynamic response to intubation.

Material And Methods: Patients ( = 86) undergoing general anesthesia were randomly stratified according to age (groups 1-4); fentanyl was administered to each patient according to the Dixon and Massey method, starting at 2 μg/kg.

Dexmedetomidine for awake craniotomy: Systematic review and meta-analysis.

Introduction: For awake craniotomy, monitored anaesthesia care (MAC) had shown relatively lower failure rates. Nevertheless, the conclusion of the appropriate anaesthetic agents, and complications, has not been proposed. Therefore, the systematic review and meta-analysis was done to compare the clinical profile, surgical outcomes, and anesthesia-related complications between dexmedetomidine-based and non-dexmedetomidine regimens during monitored anesthesia care (MAC) for this procedure.

Incidence of complications associated with deep brain stimulation surgery in patients with Parkinson's disease: An 8-year retrospective study.

Background: Various complications occur in patients undergoing deep brain stimulation (DBS) surgery. The objective of this study was to determine the incidence of complications in patients with Parkinson's disease who underwent DBS surgery and identify the risk factors, especially anesthetic factors.

Methods: A retrospective cohort study was performed between May 2015 and December 2022.

The dosage of thiopental as pharmacological cerebral protection during non-shunt carotid endarterectomy: A retrospective study.

Background: Thiopental has been used as a pharmacological cerebral protection strategy during carotid endarterectomy surgeries. However, the optimal dosage required to induce burst suppression on the electroencephalogram (EEG) remains unknown. This retrospective study aimed to determine the optimal dosage of thiopental required to induce burst suppression during non-shunt carotid endarterectomy.

Algorithmic prediction of anaesthesia manpower quantity needs: A multicentre study.

Background: A shortage of anaesthetists affects health system globally. This is a study on task-force to develop a predictive model for the appropriate number of anaesthetic providers (Y).

Methods: A cross-sectional study was performed with randomisation from every health service region across Thailand.

Incidence and Risk Factors for Perioperative Cardiovascular Complications in Spine Surgery.

An increasing number of patients are opting for spine surgery despite the associated risk of cardiovascular complications. The evidence regarding the incidence and risk factors of cardiovascular complications in spine surgery is insufficient. Therefore, we aimed to determine the incidence and risk factors for cardiovascular complications that occur perioperatively in spine surgery.

Anesthesia workforce capacity in Thailand: A multicenter study.

Background: Workforce management in anesthesia services is crucial for service quality. However, the data associated with this are lacking. Therefore, this study was done to analyze workforce and workload and to compare differences among hospital clusters in Thailand.

Analgesic efficacy of intravenous nefopam after spine surgery: a randomized, double-blind, placebo-controlled trial.

The incidence of moderate to severe pain is high among patients undergoing spinal surgery. Nefopam can be used as an adjuvant analgesic postoperatively after spine surgery. The study aimed to assess the analgesic efficacy and side effects of nefopam on 24-hour postoperative morphine consumption after spine surgery.

Unintended intraoperative awareness: An analysis of Perioperative Anesthetic Adverse Events in Thailand (PAAd Thai).

Background: Despite the improvement of anesthetic-related modalities, the incidence of unintended intraoperative awareness remains at around 0.005-0.038%.

ACUTE PHYSIOLOGY AND CHRONIC HEALTH EVALUATION (APACHE) II SCORE - THE CLINICAL PREDICTOR IN NEUROSURGICAL INTENSIVE CARE UNIT.

The APACHE II scoring system is approved for its benchmarking and mortality predictions, but there are only a few articles published to demonstrate it in neurosurgical patients. Therefore, this study was performed to acknowledge this score and its predictive performance to hospital mortality in a tertiary referral neurosurgical intensive care unit (ICU). All patients admitted to the Neurosurgical ICU from February 1 to July 31, 2011 were recruited.

Perioperative anaesthetic adverse events in Thailand (PAAd THAI) study: Incident report of perioperative convulsion.

The aim of this study was to identify the characteristics of perioperative convulsion and to suggest possible correcting strategies. The multi-centre study was conducted prospectively in 22 hospitals across Thailand in 2015. The occurrences of perioperative adverse events were collected.

Parameters Affecting Length of Stay Among Neurosurgical Patients in an Intensive Care Unit.

Aim: to determine the predictive factors on the length of stay of neurosurgical patients in the ICU setting.

Methods: all patients admitted to the neurosurgical ICU between February 1 and July 31, 2011 were recruited. Patient demographics and clinical data for each variable were collected within 30 minutes of admission.

Alternative placement of bispectral index electrode for monitoring depth of anesthesia during neurosurgery.

In neurosurgery in particular, the recommended placement of electrodes for monitoring depth of anesthesia during surgery sometimes conflicts with the surgical site or patient positioning. Therefore, we proposed this study to evaluate the agreement and correlation of bispectral index values recorded from the usual frontal area and the alternate, post-auricular areas in neurosurgery patients. Thirty-four patients scheduled for neurosurgery under general anesthesia were included.

Why don't we do enough medical research?

Objective: To locate the 5 main factors related to the scarcity of medical research.

Methods: The study was conducted at the Prasat Neurological Institute, Bangkok, Thailand, from December 1 to 15, 2006, and comprised medical staff of the institution. A questionnaire was developed that explored demographic data, evaluation of the 5 domains related to--knowledge, attitude, motivation, resources, and skills--and the requirement for research conducted.

Prediction of discharge outcome with the full outline of unresponsiveness (FOUR) score in neurosurgical patients.

To identify the diagnostic properties of the Full Outline of Unresponsiveness (FOUR) score and the discharge outcome, 318 patients were studied. The evaluators rated the patients on admission or when they had mental status alteration with the FOUR score. The course of treatment was determined based on the clinical.

Endorsement of the FOUR score for consciousness assessment in neurosurgical patients.

The Full Outline of UnResponsiveness (FOUR) score was previously developed for neurological assessment, but has not been validated in neurosurgical patients, so was compared to the Glasgow Coma Scale (GCS) in practice. Four groups of raters, expert clinicians, novice clinicians, experienced nurses, and inexperienced nurses, assessed 64 patients in awake, drowsy, stuporous, and comatose conditions to investigate rater reliability. Then, 36 patients were evaluated by 1 expert clinician and 1 from the other groups randomly to test the difference.

Evaluation of acute postoperative pain monitoring program for nurses in Thailand.

Objective: To evaluate the effectiveness of an acute postoperative pain monitoring program (APPMP) on pain knowledge, attitude, and applicability of nurses at Prasat Neurological Institute, Bangkok, Thailand.

Methods: This study was conducted from 1st March to 31st October 2008, at the Prasat Neurological Institute, Bangkok, Thailand. Thirty-five neurological nurses were recruited.

Blood glucose level in neurosurgery. Is it different between isoflurane and desflurane anesthesia?

Aim: A tight control of blood glucose is critical. We compare blood glucose level between isoflurane and desflurane in neurosurgical patients for further application.

Methods: One hundred and eight patients scheduled for neurosurgery under general anesthesia were recruited and divided into two groups; fentanyl-isoflurane-nitrous oxide based and fentanyl-desflurane-nitrous oxide based randomly.

The Thai Anesthesia Incident Monitoring study (Thai AIMS): an analysis of 21 awareness events.

Objective: To demonstrate the characteristics, outcomes, and the circumstances associated with intraoperative recall of awareness.

Material And Method: Relevant data of intra-operative recall of awareness were extracted from the Thai Anesthesia Incident Monitoring study (Thai AIMS) database of 1996 incident reports and 2537 incidents which were conducted among 51 hospitals throughout Thailand from January to June, 2007. Details regarding patients, surgical, anesthetic and systematic factors were recorded in a structured data record form.

The Thai Anesthesia Incident Monitoring Study (Thai AIMS) of endobronchial intubation: an analysis of 1996 incident reports.

Objective: To analyze the clinical course, outcomes, contributing factor, corrective and preventive strategies of accidental endobroncheal intubation (EBI) in the Thai Anesthesia Incident Monitoring Study (Thai AIMS).

Material And Method: This was a prospective descriptive multicenter study of anesthesia-related adverse incidents from 51 hospitals across Thailand from January to June 2007. Possible accidental EBI data were extracted and analyzed using descriptive statistics by 3 reviewers.

Multicentered study of model of anesthesia related adverse events in Thailand by incident report (The Thai Anesthesia Incidents Monitoring Study): results.

Objective: The Thai Anesthesia Incidents Monitoring Study (Thai AIMS) was aimed to identify and analyze anesthesia incidents in order to find out the frequency distribution, clinical courses, management of incidents, and investigation of model appropriate for possible corrective strategies.

Material And Method: Fifty-one hospitals (comprising of university, military, regional, general, and district hospitals across Thailand) participated in the present study. Each hospital was invited to report, on an anonymous and voluntary basis, any unintended anesthesia incident during six months (January to June 2007).

The Thai Anesthesia Incidents (THAI Study) of anesthetic risk factors related to perioperative death and perioperative cardiovascular complications in intracranial surgery.

Objective: To evaluate the correlations between anesthetic risk factors and perioperative cardiovascular complications as well as perioperative death within 72 hours.

Material And Method: This case controlled took the data from the Thai Anesthesia Incidents Study (THAI Study), a prospective multi-centered registry of anesthesia in Thailand. The authors included all the patients who received intracranial surgery from 20 hospitals throughout Thailand.

The Thai Anesthesia Incidents Study (THAI Study) of perioperative convulsion.

Objectives: To identify the incidence of perioperative convulsion within 24 hours, outcome, predisposing risk factors, contributing factors related to anesthesia and corrective strategies.

Material And Method: The prospective cohort study enrolled all anesthetics from twenty eligible hospitals in Thailand between March 1, 2003, and February 28, 2004. Postoperative convulsion incidents were extracted from the Thai Anesthesia Incidents Study (THAI Study) database in terms of demographic data, details of events, outcome, contributing factors related to anesthesia and corrective strategies.

Perioperative stroke and coma in Thai Anesthesia Incidents Study (THAI Study).

Objectives: To analyze perioperative stroke and coma using database of Thai Anesthesia Incidents Study (THAI Study) with regard to frequency, contributing factors, preventive and corrective strategies.

Material And Method: Details of perioperative neurological complications comprising stroke and coma in one year were recorded prospectively by attending anesthesiologists or nurse anesthetists in standardized record forms. All data were analyzed to identify contributing factors and preventive strategies.

The Thai Anesthesia Incidents Study (THAI Study) on nerve injury associated with anesthesia.

Objectives: The Thai Anesthesia Incidents Study (THAI Study) database was used to identify the incidence, outcome and contributing factors of nerve injuries associated with anesthesia in Thai people.

Material And Method: A prospective multicenter study was conducted in 20 hospital in Thailand from February 1, 2003 to January 31, 2004. All patients underwent anaesthesia were monitored for nerve injuries during the first 24 hours.