Publications by authors named "Phung-Kim Lai"
Pharm Dev Technol
May 2002
Article Synopsis
- A thermo-reversible gelling formulation of poloxamer 407 was developed to administer paclitaxel locally at tumor sites for increased efficacy.
- In vitro studies showed slow paclitaxel release from the gel, suggesting challenges due to the drug's poor solubility.
- Intratumoral administration in mice resulted in a significant delay in tumor growth and improved survival rates compared to control, highlighting the potential of this formulation for treating solid tumors.
