New naphtho[2,1-]furan-2,5-dione and isocoumarin derivatives from bambusicolous fungus .

Two new compounds, 6-hydroxy-1-(4-hydroxyphenyl)naphtho[2,1-]furan-2,5-dion () and 3-methyl-6--L-rhamnopyranosyl-2-chromen-2-one (), along with three known compounds (-) were isolated from the rare bambusicolous fungus . The structures were elucidated through the analysis of IR, NMR and HRESIMS spectrographic data. Compound exhibited cytotoxicity against HeLa, HT29, MCF-7 and PC-3 cells, but was not toxic against normal Vero cells.

Phosphatidylcholine and ceramide derivatives from white rot fungus PP17-20.

The undescribed phosphatidylcholine (), along with twelve known compounds, was isolated from the cultures of white rot fungus PP17-20. In this work the fungus was cultivated in Yeast-Malt extract medium to explore active compound production. The chemical structures were elucidated on the basis of spectroscopic and HRESIMS data.

Engleromophilane, a new broad spectrum bioactive eremophilane-type sesquiterpene from fungus.

A new eremophilane sesquiterpene, named engleromophilane () together with known eremoxylarin E () and steroids (-) were isolated from the fungus culture. The structures were deduced by the analysis of spectroscopic and MS data, together with the comparison of calculated C NMR chemical shifts and Electronic Circular Dichroism (ECD) spectra. Compound showed cytotoxic effects against Hela, PC-3, HT29 and A549 cell lines with IC in the ranges of 4.

Antiproliferative polyketides from fungus Xylaria cf. Longipes SWUF08-81 in different culture media.

Bioactive compounds from the wood-decay fungus Xylaria cf. longipes SWUF08-81, cultivated in three different culture media (GM, YM and PDB), were isolated. Their structures and stereochemistry were deduced from spectroscopic and MS data analysis, together with quantum chemical calculations of C NMR chemical shifts and electronic circular dichroism (ECD) spectra.

Hypoxylonone, a new oxa-bridged seven-membered ring analog from fungus cf. SWUF15-004.

A new oxa-bridged seven-membered ring analog, hypoxylonone (), and thirteen known compounds () were isolated from fungus cf. SWUF15-004. The structures were elucidated by the analysis of spectroscopic (IR, 1 D and 2 D NMR), HRESIMS and X-ray diffraction (MoKα) data.

Anti-inflammatory and anti-proliferative activities of chemical constituents from fungus Biscogniauxia whalleyi SWUF13-085.

The fungus Biscogniauxia whalleyi SWUF13-085 from the Graphostomataceae family was studied for potential anti-inflammatory and anticancer agents. A diverse array of natural products was identified. Six of which were undescribed compounds, including xylariterpenoids L-N, (1R,2S,6R,7S)-1,2-dihydroxy-α-bisabolol, 6-[(1R)-1-hydroxy-1-methyl-2-propenyl]-4-methoxy-3-methyl-2H-pyran-2-one and (1R*,4S*,5S*,7S*,10R*)-guaia-11 (12)-en-7,10-diol.

Anti-inflammatory and cytotoxic agents from sp. SWUF09-62 fungus.

The ongoing search for anti-cancer agents from microorganisms led to the isolation of four new compounds including 6-ethyl-8-hydroxy-4-chromen-4-one (), 6-ethyl-7,8-dihydroxy-4-chromen-4-one (), (3)-3,4-dihydro-8-hydroxy-7-methoxy-3-methylisocoumarin () and (3)-3,4-dihydro-5,7,8-trihydroxy-3-methylisocoumarin (), together with eleven known compounds (-) from sp. SWUF09-62 fungus. The chemical structures were deduced from IR, 1D and 2D NMR, and MS data.