Publications by authors named "Phitsanu Tulayakul"

The aim of this study was to analyze and compare the Hg, Pb, Cd, and Mn levels in egg feed, soil, and water among laying hens, laying ducks, and free-grazing duck farms in contaminated and uncontaminated areas. This study revealed that the Hg concentration in the eggs of free-grazing ducks was significantly greater than that in the eggs of laying hens and ducks in both contaminated and uncontaminated areas. However, the Pb and Mn levels in the eggs of laying ducks and free-grazing ducks were significantly greater than those in the eggs of laying hens in the contaminated area.

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After publication of the article, the authors received comments from a member of the editorial board who is an expert in the field of adenovirus concerning figures and references that should be included in the paper [...

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Background And Aim: Salmonellosis is a significant foodborne disease that causes serious illness in the gastrointestinal of humans and it is a public health problem worldwide. This study aimed to determine spp. in animal feeds, its characteristic, serovar identification, genotyping, and drug sensitivity.

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Dietary fat can alter host metabolism and gut microbial composition. Crocodile oil (CO) was extracted from the fatty tissues of Crocodylus siamensis. CO, rich in monounsaturated- and polyunsaturated fatty acids, has been reported to reduce inflammation, counter toxification, and improve energy metabolism.

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Article Synopsis
  • Metagenomics has been effective in finding new pathogens and monitoring outbreaks, helping identify various viruses in asymptomatic long-tailed macaques from Thailand.
  • A specific workflow detected novel astroviruses, enteroviruses, and adenoviruses in fecal samples, revealing a potential new adenovirus that can infect both monkeys and humans.
  • The study underscores the importance of ongoing zoonotic surveillance in areas where humans and animals coexist to prevent the emergence of new pathogens.
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  • Japanese encephalitis virus (JEV) is a common cause of encephalitis in Asia, transmitted to humans primarily through mosquito bites, with pigs and birds serving as main hosts.
  • This study found JEV neutralizing antibodies in non-human primates (NHPs) and humans in Thailand, indicating natural infection and transmission between species, with seropositivity rates of 14.7% in monkeys and up to 45.2% in humans.
  • The results suggest a need for ongoing serological studies at the animal-human interface to monitor JEV, especially given the higher infection rates in older humans.
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The liver is a key organ governing body energy metabolism. Dietary fats influence energy metabolism and mitochondrial functioning. Crocodile oil (CO) is rich in mono- and polyunsaturated fatty acids that contain natural anti-inflammatory and healing properties.

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is a foodborne pathogen exhibiting a high mortality rate. In addition to the robust tolerance to environmental stress, the ability of to develop biofilms increases the risk of contaminating food processing facilities and ultimately foods. This study aims to develop a synergistic approach to better control biofilms using nisin, the only bacteriocin approved as a food preservative, in combination with gallic-acid-rich food plant extracts.

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Crocodile oil (CO) is rich in monounsaturated fatty acids and polyunsaturated fatty acids. The antioxidant activity and cognitive effect of monounsaturated fatty acids and polyunsaturated fatty acids have been largely reported. This work aimed to investigate the effect of CO on antioxidant activity and cognitive function in rats.

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Background: Dietary fat composition is a potential major factor affecting energy metabolism. Crocodile oil (CO) is rich in mono- and poly-unsaturated fatty acids exhibiting anti-inflammatory and healing properties.

Aim: This study investigated different levels of CO consumption on alterations and expression of proteins involved in energy metabolism in rats.

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is a major nosocomial pathogen that frequently forms biofilms on indwelling medical devices. This study aimed to investigate the synergistic antimicrobial and antibiofilm activities of octyl gallate (OG) in combination with penicillin and bacitracin against . Antimicrobial synergy was assessed by conducting checkerboard titration assays, and antibiofilm activity was determined with biofilm assays and fluorescence microscopy analysis.

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Crocodile oil is a highly effective treatment for ailments ranging from skin conditions to cancer. However, the effects of the oil on liver detoxification pathways are not well studied. This study aimed to investigate the effects of crocodile oil on the detoxification enzyme activities and the mRNA expressions of cytochrome P450 1A2 (CYP1A2), cytochrome P450 2E1 (CYP2E1), and glutathione S-transferase (GST) in rats.

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Simian adenoviruses are in the genus of the family . This family is composed of non-enveloped, double-stranded DNA viruses that infect a wide range of animals. Mastadenoviruses infect mammals, including non-human primates and humans.

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  • Gold-mining activities are causing heavy metal pollution (Hg, Pb, Mn) that threatens public health in nearby areas, prompting a study in northern Thailand focused on chicken and duck farms.
  • The study revealed that concentrations of these heavy metals were significantly higher in free-grazing ducks and their eggs located within 25 km of the mine compared to those farther away, indicating severe contamination issues.
  • Health risks from heavy metal exposure were highlighted, particularly a higher incremental lifetime cancer risk for local populations, especially affecting younger age groups, underscoring the need for ongoing health surveillance and control measures for poultry near the mine.
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Background And Aim: Consumption of fatty acids (FA) can alter hepatic energy metabolism and mitochondrial function in the liver. Crocodile oil (CO) is rich in mono-and polyunsaturated FAs, which have natural anti-inflammatory and healing properties. In rat livers, we investigated the effect of CO on mitochondrial function for energy homeostasis.

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This study aimed to determine the incidence of leptospirosis and melioidosis in long-tailed macaques (Macaca fascicularis) in Thailand. Serum samples from 223 monkeys were subjected to the Lepto Latex Test and indirect hemagglutination (IHA) test to detect antibodies against Leptospira spp. and Burkholderia pseudomallei.

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Background And Aim: The crocodile is a model for studying relevant sources of environmental contamination. They were determined an appropriate biomonitoring species for various toxins. The cytosolic and microsomal fraction of crocodiles plays a role in detoxifying xenobiotics.

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Public-private partnerships (PPPs) in the veterinary domain are joint approaches in which public veterinary services and private actors such as private veterinarians, producers' associations, or private companies work together to address complex animal health challenges. They are implemented worldwide and can help to strengthen the capacities of veterinary services, but few have been evaluated. None of the evaluations developed in the veterinary domain explicitly addressed PPPs, their complex program design, their evolving governance, and coordination system, and their impacts.

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Several consequences of health effects from municipal solid waste caused by carcinogenic and noncarcinogenic metals have been recognized. The water quality index (WQI) in the groundwater around this landfill is 2945.58, which is unacceptable for consumption.

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The proposes of this study were to compare THg (total mercury), Pb(Lead), Cd(Cadmium), and Mn (Manganese) contamination in poultry blood between polluted areas (≤ 25 km) and unpolluted areas (> 25 km) adjacent to the largest gold mining in northern Thailand. The THg level in the free-grazing duck in polluted areas was significantly higher than unpolluted area. Both THg and Pb levels in free-grazing duck were also highest in polluted areas.

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Currently, Thai livestock is rapidly expanding, especially the production of ruminants, chicken, and swine. The improper use of antibiotics will probably lead to an antimicrobial resistance problem. It has long been suspected that wastewater released from swine farms is a crucial aspect of the spread of antimicrobial resistance to the environment.

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Article Synopsis
  • * This study investigated the exposure of various macaque species in Thailand to mosquito-borne flaviviruses and alphavirus by testing their blood for antibodies against dengue, Zika, and chikungunya viruses.
  • * Results showed that stump-tailed macaques had antibodies for dengue and Zika, while long-tailed and pigtailed macaques lacked such antibodies; however, one long-tailed macaque had antibodies for chikungunya, indicating a potential risk of these viruses to human health due to increasing human-wildlife interactions. *
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This study aimed to compare the metabolism of detoxification liver enzymes activity of CYP1A2, CYP2E1, the GST enzymes activity for class pi, mu, alfa, and the universal GST between crocodile and livestock, plus the relationship of these two enzyme activities in the crocodile. Interestingly, the CYP1A2 and CYP2E1 were existent in the freshwater crocodile livers microsomal enzyme activities, and these two enzymes could be determined in both pig and chicken. Also, the universal GST, alpha, mu, and pi class of phase II were presented in the crocodile liver cytosolic fractions, and these three enzymes could also be found in pig and chicken.

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Zinc, Pb, Cd, Mn, Fe, Cr, and Cu levels in duck meat from large-scale farms have been found to be significantly higher than those from free-grazing duck farms. Zinc, Co, Mn, Cr, and Cu contamination levels in duck liver from large-scale farms were significantly higher than those from free-grazing farms; only Cd in duck liver from free-grazing farms was higher than in liver samples from large-scale farms at P < 0.05.

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The metabolism of aflatoxin B (AFB) generates reactive oxygen species (ROS) that destroys hepatocytes. Meanwhile, astaxanthin (AX) is known to have stronger antioxidative activity than other carotenoids. This study aimed to investigate hepatoprotective role of AX from AFB-induced toxicity in rat by histopathological study and immunohistochemistry of Cu/Zn-SOD (SOD1) which acts as the first enzyme in antioxidative reaction against cell injury from ROS.

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