Acute ketone monoester (KE) supplementation may affect exercise performance, particularly in cycling, though results are inconsistent due to various factors like dose and athlete experience.
A study with 23 trained cyclists tested whether KE ingestion affected power output in a 20-minute cycling time trial compared to a placebo, with a significant increase in blood ketones after KE.
Results showed that mean power output was actually 2.4% lower after KE supplementation compared to the placebo, indicating that KE may impair performance under certain conditions.