Patients' and carers' views on research priorities in prehabilitation for cancer surgery.

Introduction: The views of patients and carers are important for the development of research priorities. This study aimed to determine and compare the top research priorities of cancer patients and carers with those of multidisciplinary clinicians with expertise in prehabilitation.

Materials And Methods: This cross-sectional study surveyed patients recovering from cancer surgery at a major tertiary hospital in Sydney, Australia, and/or their carers between March and July 2023.

How learners learn: A new microanalytic assessment method to map decision-making.

Background: Microanalytic techniques have shown considerable potential as avenues for understanding learning in a range of learning contexts. If a microanalytic approach is to be tested for utility, a suitable learning context is required. We chose problem-based learning (PBL) tutorials as our context.

In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand.

Src signalling and transduction are directly involved in cell growth, cell cycle, malignant transformation and cell migration, providing therapeutic opportunities through inhibition of Src. Here we report virtual screening for novel compounds that inhibit the Src-SH3 protein-protein interaction with a proline-rich peptide ligand. Computational docking of the ZINC compound database was performed using GOLD.