Publications by authors named "Phillipe Lemey"
The effectiveness of poultry vaccination in preventing the transmission of highly pathogenic avian influenza viruses (AIVs) has been debated, and its impact on wild birds remains uncertain. Here, we reconstruct the movements of H5 subtype AIV lineages among vaccinated poultry, unvaccinated poultry, and wild birds, worldwide, from 1996 to 2023. We find that there is a time lag in viral transmission among different host populations and that movements from wild birds to unvaccinated poultry were more frequent than those from wild birds to vaccinated poultry.
View Article and Find Full Text PDFBotswana, like the rest of the world, has been significantly impacted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In December 2022, we detected a monophyletic cluster of genomes comprising a sublineage of the Omicron variant of concern (VOC) designated as B.1.
View Article and Find Full Text PDFHighly pathogenic avian influenza virus (HPAIV) A H5, particularly clade 2.3.4.
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- The COVID-19 epidemic in the U.S. went largely unnoticed due to a lack of testing, with New Orleans experiencing one of the earliest outbreaks during Mardi Gras.
- Researchers sequenced SARS-CoV-2 genomes in Louisiana and found that the virus had limited diversity, indicating a single introduction led to most early cases.
- The study revealed that SARS-CoV-2 was likely present in New Orleans before Mardi Gras, and the event significantly contributed to the rapid spread of the virus, highlighting the impact of large gatherings on epidemics.
Article Synopsis
- The early COVID-19 outbreak in the U.S. was largely unnoticed due to insufficient testing and prevention measures, particularly noticeable in New Orleans during Mardi Gras.
- Genetic analysis of SARS-CoV-2 in Louisiana revealed that the virus had limited diversity at first and that one initial introduction was responsible for most early transmissions.
- The presence of the virus in New Orleans before Mardi Gras and the festival's large gatherings significantly sped up the spread, contributing to localized epidemics across the Southern U.S.
Epidemiologically-linked HIV-1 transmission cohorts serve as excellent models to study HIV disease progression. The actual relationship between viral variability and HIV disease outcome can be extrapolated only through such rare epidemiologically linked HIV-1-infected cohorts. We present here a cohort of three patients with the source termed donor A (a nonprogressor) and two recipients B and C.
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