Publications by authors named "Phillip Wagner"

Background: Overuse of preoperative cardiac testing contributes to high healthcare costs and delayed surgeries. A large body of research has evaluated factors associated with variation in preoperative cardiac testing. However, patient, provider, and system-level factors associated with variation in testing have not been systematically studied.

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Background: Infectious Disease Society of America (IDSA) guidelines recommend the usage of a loading dose when using vancomycin for seriously ill patients. While the relationship between vancomycin and nephrotoxicity is the focus of many studies, few studies have examined the relationship between vancomycin loading doses and nephrotoxicity.

Methods: We performed a retrospective cohort study examining vancomycin dosing for internal medicine teaching services' patients over the 2014-15 academic year at one academic medical center.

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Case: We present the case of a 49-year-old woman who underwent a 237-day hunger strike on the streets of Pittsburgh, Pennsylvania. Despite medical supervision and appropriate micronutrient supplementation, including higher-than-recommended dosing of oral thiamine, the patient developed Wernicke's Encephalopathy and subsequent Korsakoff Syndrome. She is now permanently impaired.

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Understanding typical variation of vertical jump (VJ) performance and confounding sources of its typical variability (i.e., familiarization and competitive level) is pertinent in the routine monitoring of athletes.

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Objectives: Small for gestational age (SGA) is considered as an indicator of intrauterine growth restriction, and multiple maternal and newborn characteristics have been identified as risk factors for SGA. This knowledge is mainly based on measures of average association (ie, OR) that quantify differences in average risk between exposed and unexposed groups. Nevertheless, average associations do not assess the discriminatory accuracy of the risk factors (ie, its ability to discriminate the babies who will develop SGA from those that will not).

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The goal of this study was to assess (a) the eccentric rate of force development, the concentric force, and selected time variables on vertical performance during countermovement jump, (b) the existence of gender differences in these variables, and (c) the sport-specific differences. The sample was composed of 189 males and 84 females, all elite athletes involved in college and professional sports (primarily football, basketball, baseball, and volleyball). The subjects performed a series of 6 countermovement jumps on a force plate (500 Hz).

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The development of power lies at the foundation of all movement, especially athletic performance. Unfortunately, training programmes of athletes often seek to improve cardiovascular endurance through activities such as distance training that are detrimental for the performance of power athletes, rather than using other means of exercise. Performance decrements from continuous aerobic training can be a result of inappropriate neuromuscular adaptations, a catabolic hormonal profile, an increased risk for overtraining and an ineffective motor learning environment.

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With the increasing use of allograft tissue and the recent infections found in patients undergoing surgical procedures, the current practices that prepare grafts for implantation must be examined. Initially, most tissue banks harvest allografts aseptically. There are many steps in the different techniques of preparation and processing of allograft tissue.

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Glucosamine and chondroitin are alternative solutions to previous pharmaceutical options for the treatment of osteoarthritis. This article describes the mechanisms of action, pharmacokinetics, recent findings, and upcoming studies of these two natural remedies. The majority of studies on the mechanisms behind glucosamine and chondroitin have been performed in vitro or on animal models; however, the results have shown favorable effects on the balance between cartilage matrix synthesis and degradation.

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