Predictive Value of V̇O in Adult Congenital Heart Disease in Comparison with Heart Failure with Reduced Ejection Fraction.

Background: Peak oxygen consumption (V̇O ) is used to predict outcomes and the timing of transplantation in patients with heart failure with reduced ejection fraction (HFrEF); V̇O also has predictive utility in patients with adult congenital heart disease (ACHD). However, the predictive value of a given V̇O in patients with ACHD compared to those with HFrEF, especially after adjustment for age and sex, is not clear.

Methods: To address this, we performed a longitudinal cohort study comparing patients with ACHD to patients with HFrEF.