Background And Aims: Limited data exist on the cardiovascular manifestations and risk factors in people hospitalized with COVID-19 from low- and middle-income countries. This study aims to describe cardiovascular risk factors, clinical manifestations, and outcomes among patients hospitalized with COVID-19 in low, lower-middle, upper-middle- and high-income countries (LIC, LMIC, UMIC, HIC).
Methods: Through a prospective cohort study, data on demographics and pre-existing conditions at hospital admission, clinical outcomes at hospital discharge (death, major adverse cardiovascular events (MACE), renal failure, neurological events, and pulmonary outcomes), 30-day vital status, and re-hospitalization were collected.
Aim To study features of diagnosis and treatment of acute myocardial infarction (AMI) in Russian hospitals, results of the treatment, and early and late outcomes (6 and 12 months after AMI diagnosis); to evaluate the consistence of the treatment with clinical guidelines; and to evaluate patients' compliance with the treatment.Material and methods The program was designed for 3 years, including 24 months for recruitment of patients to the study. The study will include 10, 000 patients hospitalized with a confirmed diagnosis (I21 according to ICD-10) of ST segment elevation acute myocardial infarction (MI) (STEMI) or non-ST segment elevation MI (NSTEMI) based on criteria of the European Society of Cardiology Guidelines on Forth Universal Definition of Myocardial Infarction (2018).
View Article and Find Full Text PDFThe literature review presents the possibilities of using non - steroidal anti - inflammatory drugs (NSAIDs) for polymorbid pathology. The mechanism of NSAIDs action, risk factors for the development of undesirable effects on the cardiovascular, digestive, urinary and other systems are considered; prevention measures and drug selection options are discussed, NSAIDs prescribing algorithm is considered.
View Article and Find Full Text PDFThe Purpose: To study effect of controllable moderate hypothermia on system of hemostasis in newborns with hypoxemic ischemic encephalopathy.
Materials And Methods: The retrospective analysis was carried out concerning 38 medical records of newborns with acute hypoxia of fetus (group I), 12 medical records of newborns with acute hypoxia of fetus against the background of chronic hypoxia of fetus (group II), 20 healthy newborns (group III) and 20 healthy adults. The thromboelastography was implemented in three stages: at first, third and sixth days of life of newborns.
A comparative estimation was conducted to assess the prevalence of genotypes and alleles of the (353)R>Q polymorphism of the coagulation factor FVII gene between a group of the Russian adolescents with essential arterial hypertension and a group of Russian adolescents without such health problems. The RR genotype was diagnosed in 55 adolescents (75.34%) of the control group and in 99 adolescents (84.
View Article and Find Full Text PDFPurpose: The purpose of this study was to report the preliminary experience of a modified transcervical carotid angioplasty and stenting (CAS) technique with filter protection and flow reversal only during filter placement in patients unsuitable for transfemoral CAS and at high risk for carotid endarterectomy (CEA).
Patients And Methods: Twenty-five of 132 patients, aged 75 to 86 years old, with severe carotid stenosis had been selected. Eighteen patients had transient ischemic attacks (TIAs) in the last month and seven patients were asymptomatic.
Aim: The aim of this study was to use the maximum of all the protective measures to make carotid angioplasty and stenting (CAS) a safe procedure.
Methods: Twenty patients with severe carotid disease have been treated. These patients were considered as high risk for carotid endarterectomy and not suitable for transfemoral CAS for anatomic reasons.