Sex differences in the effect of progesterone after controlled cortical impact in adolescent mice: a preliminary study.

Object: While progesterone has been well studied in experimental models of adult traumatic brain injury (TBI), it has not been evaluated in pediatric models. The study of promising interventions in pediatric TBI is important because children have the highest public health burden of such injuries. Therapies that are beneficial in adults may not necessarily be effective in the pediatric population.

Chronic gliosis and behavioral deficits in mice following repetitive mild traumatic brain injury.

Object: With the recent increasing interest in outcomes after repetitive mild traumatic brain injury (rmTBI; e.g., sports concussions), several models of rmTBI have been established.