Background: Itopride, a mixed D2 antagonist and cholinesterase inhibitor, has prokinetic effects on gastric motility. The Leuven Postprandial Distress Scale is a validated patient-reported outcome instrument for functional dyspepsia (FD) postprandial distress syndrome (PDS). We aimed to use the LPDS to assess treatment outcome in PDS and PDS/EPS (epigastric pain syndrome).
View Article and Find Full Text PDFClin Gastroenterol Hepatol
August 2021
Background & Aims: Functional dyspepsia (FD) is subdivided into postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) according to the Rome III consensus. In clinical practice, there is a major overlap between these subgroups. The Rome IV criteria included postprandially occurring symptoms in the PDS subgroup.
View Article and Find Full Text PDFWe report a rare case of purely retrograde stenosing stricture of the sigmoid descending colonic junction fortuitously diagnosed during the waning of a failed virtual colonoscopy in a 69-year-old patient. The rather asymptomatic patient was addressed to investigate a positive fecal occult blood test. He had suffered a single acute colonic diverticulitis episode 19 years before.
View Article and Find Full Text PDFWe report a very rare case of acute congestive ischaemic colitis of the left colon caused by brutal decompensation of an uncommon arteriovenous malformation (AVM) in the territory of the inferior mesenteric artery (IMA) in a 45-year-old male patient. The patient presented with severe abdominal pain in the left iliac fossa and abundant mucoid stools. The diagnosis of congestive colitis was made by optical colonoscopy but the full diagnosis of the responsible AVM in the IMA territory was made by contrast-enhanced multidetector CT scan combined with colour Doppler ultrasound.
View Article and Find Full Text PDFWe report two cases of elderly patients presenting with life-threatening complications due to inadvertent accidental ingestion of blister pill packs (BPPs). The first patient presented with obstruction followed by anemia and finally perforation of the small bowel. The second presented with rapidly lethal mediastinitis due to a large perforation of the lower esophagus.
View Article and Find Full Text PDFBackground: Immunosuppressive drugs may prevent or partially reverse progression of renal AA-amyloidosis, a rare complication of Crohn's disease, often fatal due to renal failure.
Materials And Methods: The clinical, biological and pathological data of 16 patients treated since 1976 were reviewed. Serum amyloid A was determined in surviving patients.
We present the case of a 26-year-old man with schizoid personality disorder who suffered from a very focal and transparietal necrosis of the sigmoid after an overdose of atypical neuroleptics. This is a singular, rather unknown and potentially lethal side effect of these drugs. The physiopathology of this complication is multifactorial.
View Article and Find Full Text PDFWe report a very rare case of internal hernia of the small bowel through a large congenital defect of the falciform ligament. A complete preoperative diagnosis was possible by 64-row multi-detector row computerized tomography. The identification of the characteristic anatomic features and landmarks of the obliterated umbilical vein-ligamentum teres-was the diagnostic key.
View Article and Find Full Text PDFIn contrast with their colonic equivalents, noncolonic diverticula of the gastro-intestinal tract are much rarer and an uncommon site of inflammation. Symptoms and signs are generally nonspecific and before the advent and development of CT, clinical and radiological diagnosis was very difficult. As a result laparotomy was carried out in most cases without correct preoperative diagnosis.
View Article and Find Full Text PDF