Kinetic eGFR and Novel AKI Biomarkers to Predict Renal Recovery.

Background And Objectives: Prompt recognition of severe renal impairment could improve the early management of critically ill patients. We compared the value of kinetic eGFR, plasma neutrophil gelatinase-associated lipocalin (NGAL), and urine tissue inhibitor of metalloproteinase-2 and urine insulin-like growth factor-binding protein 7 ([TIMP-2]*[IGFBP7]) in predicting short-term recovery from AKI and major adverse kidney events.

Design, Setting, Participants, & Measurements: During the 6-month study period, 245 patients were admitted to our intensive care unit.

Interest of cystatin C in screening diabetic patients for early impairment of renal function.

We compared cystatin C, creatinine, and the Cockroft formula for assessment of early renal failure, defined as a (51)Cr-EDTA clearance < 80 mL/min, in 89 diabetic patients with various degrees of renal impairment (glomerular filtration rate [GFR], 11.4 to 196.5 mL/min).

Determination of myoglobin: comparative evaluation of the new automated VIDAS assay with two other immunoassays.

Objectives: Myoglobin provides the earliest indication of acute myocardial infarction. In this study, the new myoglobin assay for the VIDAS system (bioMérieux) was evaluated.

Design And Methods: This assay, using an enzyme-linked fluorescent immunoassay (ELFIA) method, was compared with the Olympus immunoturbidimetric method and with another immunometric method (Immulite turbo) using an enzyme-linked chemiluminescent immunoassay (CLIA).