Giant unilamellar vesicles (GUVs) are increasingly used as a versatile research tool to investigate membrane structure, morphology and phase state. In these studies, GUV preparation is typically enhanced by an externally applied electric field, a process called electroformation. We find that upon osmotic deflation, GUVs electroformed from charged and neutral lipids exhibit inward pointing lipid nanotubes, suggesting negative spontaneous curvature of the membrane.
View Article and Find Full Text PDFPurpose: To design a phantom capable of mimicking human respiration to serve as a testing platform for correction of the static and time-evolving magnetic field distortions typically encountered in MRI of the spinal cord.
Methods: An inflation system to mimic the air variation of the human lungs was constructed. The inflation system was linked to a phantom containing synthetic lungs and an ex vivo human spine.