Publications by authors named "Philippe Boyer"

Article Synopsis
  • Ventilator-associated pneumonia (VAP) is a common infection in patients on mechanical ventilation, and this study looks into the gut microbiota's role in its development, compared to oropharyngeal and lung microbiota.
  • Researchers analyzed the gut microbiota of 42 ICU patients, finding that while the overall diversity of bacteria (α-diversity) was similar, the specific composition (β-diversity) differed between those who developed VAP and those who did not.
  • The study suggests that certain gut fungal species may influence the likelihood of developing VAP and encourages further research on how gut microbiota might impact lung infections in critically ill patients.
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Background: Hyperoxia is associated with increased morbidity and mortality in the intensive care unit. Classical noninvasive measurements of oxygen saturation with pulse oximeters are unable to detect hyperoxia. The Oxygen Reserve Index (ORI) is a continuous noninvasive parameter provided by a multi-wave pulse oximeter that can detect hyperoxia.

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A highly sensitive refractive index sensor is proposed by using the resonant coupling of a Tamm state to a Fabry-Perot resonance in slits periodically pierced in a metal film. This new hybrid resonance exists at the interface between a dielectric Bragg mirror and a subwavelength metal grating. Contrary to a classic Tamm plasmon, it is sensitive to the ambient media refractive index due to its confinement inside the grating slits.

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Background: From a physiological viewpoint, changes in end-tidal carbon dioxide (EtCO) could be a simple, noninvasive, and inexpensive way to monitor changes in cardiac index. This study aimed to assess the utility of changes in EtCO as a marker of fluid responsiveness after volume expansion in the operating room.

Methods: A prospective observational study was conducted in a tertiary university teaching hospital, from August 2018 to February 2019.

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Background: Dynamic arterial elastance (Eadyn), defined as the ratio between pulse pressure variations and stroke volume variations, has been proposed to assess functional arterial load. We evaluated the evolution of Eadyn during volume expansion and the effects of neosynephrine infusion in hypotensive and preload-responsive patients.

Methods: In this prospective bicentre study, we included 56 mechanically ventilated patients in the operating room.

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Purpose: To determine whether augmented renal clearance (ARC) impacts negatively on piperacillin-tazobactam unbound concentrations in critically ill patients receiving 16 g/2 g/day administered continuously.

Material And Methods: Fifty nine critically ill patients without renal impairment underwent 24-h creatinine clearance (Cr) measurement and therapeutic drug monitoring during the first three days of antimicrobial therapy by piperacillin-tazobactam. The main outcome was the rate of piperacillin underexposure, defined by at least one of three samples under 16 mg/L.

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Bloch surface waves (BSWs) are recently developing alternative to surface plasmon polaritons (SPPs). Due to dramatically enhanced propagation distance and strong field confinement these surface states can be successfully used in on-chip all-optical integrated devices of increased complexity. In this work we propose a highly miniaturized grating based BSW coupler which is gathering launching and directional switching functionalities in a single element.

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A two-dimensional periodic sub-wavelength array of vertical dielectric cylinders on a glass substrate is studied numerically using three different electromagnetic approaches. It is shown that such structure can present a narrow-band spectral resonance characterized by large angular tolerances and 100% maximum in reflection. In particular, in a two-nanometer spectral bandwidth the reflectivity stays above 90% within angles of incidence exceeding 10 degrees for unpolarized light.

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Objective: The aim of this study was to determine the frequency and characteristics of antisynthetase syndrome (ASS) revealed by polyarthritis.

Methods: First we conducted a retrospective single-centre study to assess the frequency of ASS patients who presented with polyarthritis without pulmonary and/or muscle symptoms. Secondly, we conducted a larger, multicentre study in order to describe the clinical characteristics of these patients.

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We deduce by the monomode modal method the analytical expressions of the transmission and reflection Jones matrices of an infinitely conducting metallic screen periodically pierced by subwavelength holes. The study is restricted to normal incidence and to the case of neglected evanescent fields (far-field), which covers many common cases. When only one nondegenerate mode propagates in cavities, they take identical forms to those of a polarizer, with Fabry-Perot-like spectral resonant factors depending on the bigrating parameters.

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We extend the differential theory to anisotropic cylindrical structures with an arbitrary cross section. Two cases have to be distinguished. When the anisotropic cylinders do not contain the origin, the scattering matrix of the device is calculated from the extended differential theory with the help of the scattering matrix propagation algorithm.

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We propose a study of a generalized Airy-like formula of the transmittance through planar resonators. A complete and analytical analysis of total transmission conditions is given according to physical parameters. The homogeneous problem related to free oscillations of resonators, which leads to complex resonance frequencies and quality factors, is also resolved.

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A fully analytical theory is developed to derive the field diffracted by an infinitely long circular cylinder made of an arbitrary anisotropic homogeneous material, illuminated by an arbitrary plane wave.

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Using two different modal methods, the multipole method and the more recent fast Fourier factorization method, we exhibit and explain a core mode transition induced by avoided crossing between a core localized leaky mode and an high-index cylinder leaky mode in anti-resonant reflecting optical waveguide microstructured optical fibers (ARROW MOFs). Due to its wavelength selectivity and to the leaky nature of the involved modes, this transition doesn't seem to have already been described in detail and analyzed as done in this work in spite of several already published studies on core mode dispersion properties. The main properties of this transition are also described.

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The differential theory of diffraction by arbitrary cross-section cylindrical objects is developed for the most general case of an incident field with a wave vector outside the cross-section plane of the object. The fast Fourier factorization technique recently developed for studying gratings is generalized to anisotropic and/or inhomogeneous media described in cylindrical coordinates; thus the Maxwell equations are reduced to a first-order differential set well suited for numerical computation. The resolution of the boundary-value problem, including an adapted S-matrix propagation algorithm, is explained in detail for the case of an isotropic medium.

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The diffraction of an electromagnetic wave by a cylindrical object with arbitrary cross section is studied by taking advantage of recent progress in grating theories. The fast Fourier factorization method previously developed in Cartesian coordinates is extended to cylindrical coordinates thanks to the periodicity of both the diffracting object and the incident wave with respect to the polar angle theta. Thus Maxwell equations in a truncated Fourier space are derived and separated in TE and TM polarization cases.

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