Publications by authors named "Philippe Babe"

Background: Deprivation generates many health inequalities. This has to be taken in account to enhance appropriate access to care. This study aimed to develop and validate a pediatric individual-level index measuring deprivation, usable in clinical practice and in public health.

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Introduction: Bronchiolitis is the leading cause of hospitalization for infants but its economic burden is not well documented. Our objective was to describe the clinical evolution and to assess the 1-month cost of a first episode of acute bronchiolitis presenting to the emergency department (ED).

Methods: Our study was an epidemiologic analysis and a cost study of the cohort drawn from the clinical trial GUERANDE, conducted in 24 French pediatric EDs.

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On July 14, 2016, a terrorist attack by truck occurred in Nice, France, during the traditional fireworks for Bastille Day. The authors present the point of view of the doctors from Lenval University Children's Hospital, which is located near the attack place and which had to manage 47 casualties, including 12 adults.

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Article Synopsis
  • Acute bronchiolitis is a major reason for hospitalizations in infants, and previous research suggested limited effectiveness of nebulized hypertonic saline (HS) treatment in emergency settings.
  • The GUERANDE study was a large, multicenter clinical trial that aimed to determine if nebulized HS could reduce hospital admissions for infants experiencing their first acute bronchiolitis episode.
  • Results showed no significant difference in hospital admission rates between the HS group (48.1% admitted) and the normal saline (NS) group (52.2% admitted), although the HS group did show greater improvement in respiratory distress symptom scores.
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Importance: The procalcitonin (PCT) assay is an accurate screening test for identifying invasive bacterial infection (IBI); however, data on the PCT assay in very young infants are insufficient.

Objective: To assess the diagnostic characteristics of the PCT assay for detecting serious bacterial infection (SBI) and IBI in febrile infants aged 7 to 91 days.

Design, Setting, And Participants: A prospective cohort study that included infants aged 7 to 91 days admitted for fever to 15 French pediatric emergency departments was conducted for a period of 30 months (October 1, 2008, through March 31, 2011).

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