Publications by authors named "Philipp von Zaluskowski"
Unlabelled: α-Glucan phosphorylases contribute to degradation of glycogen and maltodextrins formed in the course of maltose metabolism in bacteria. Accordingly, bacterial α-glucan phosphorylases are classified as either glycogen or maltodextrin phosphorylase, GlgP or MalP, respectively. GlgP and MalP enzymes follow the same catalytic mechanism, and thus their substrate spectra overlap; however, they differ in their regulation: GlgP genes are constitutively expressed and the enzymes are controlled on the activity level, whereas expression of MalP genes are transcriptionally controlled in response to the carbon source used for cultivation.
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- A study compared the gene expression of Corynebacterium glutamicum with and without the transcriptional regulator AtlR, identifying eight genes with significantly higher mRNA levels in the mutant strain.
- Four of these genes (xylB, rbtT, mtlD, sixA) are closely linked to atlR and are organized into operons that suggest a coordinated transcriptional regulation.
- Growth experiments indicated that wild-type C. glutamicum metabolizes D-arabitol effectively, which aids subsequent growth on D-mannitol, and that the proteins XylB, RbtT, and MtlD are critical for D-arabitol metabolism, whereas the absence of AtlR causes increased metabolic activity of these