Fibular free flap (FFF) is the main reconstructive choice for large mandibular defects. Recent improvements have been made regarding planning and surgical procedure, but choice of osteosynthesis material (OSM) for segment-fixation remains controversial. A retrospective cohort study obtained clinical and radiological data from FFF-patients.
View Article and Find Full Text PDFAfter several years of negative phase III trials in gastric and esophageal cancer, a significant breakthrough in the treatment of metastatic adenocarcinomas of the gastroesophageal junction (GEJ) and stomach (GC) is now becoming evident with the emerging of precision oncology and implementation of molecular targets in tumor treatment. In addition, new generation studies such as umbrella and basket trials are focused on these molecular targets, which makes an early molecular diagnosis based on IHC/ISH and NGS necessary. The required companion diagnostics of Her2neu overamplification or PD-L1 expression is based on immunohistochemistry (IHC) or additionally in situ hybridization (ISH) in case of an IHC Her2neu score of 2+.
View Article and Find Full Text PDFObjectives: Over the last few years several offers in- and outpatient creative therapy interventions for cancer patients have been developed, implemented and researched. This article describes the content, concept and structure of art therapy interventions based on painting or drawing as well as some further methodical procedures and research results of art therapy in the field of psycho-oncology.
Methods: We searched electronic databases for papers published between 1987 and March 2009 on painting or drawing based art therapy interventions in oncology.