Publications by authors named "Philipp C Jacobi"
Purpose: To assess the practical feasibility and signal quality of axial length measurements by partial coherence laser interferometry in silicone oil-filled eyes with previous complicated vitreoretinal surgery.
Settings: Department of Ophthalmology, University Cologne, Cologne, Germany.
Methods: Using a Zeiss IOLMaster, axial length measurements and signal-to-noise ratios of optical biometry in silicone oil-filled eyes (n=45) and contralateral eyes without tamponade (n=41) were analyzed.
Purpose: To evaluate the feasibility and limits of neodymium:YAG (Nd:YAG) laser capsulotomy in eyes with persistent endotamponade.
Setting: Department of Ophthalmology, University Cologne, Cologne, Germany.
Methods: In this consecutive series, an Nd:YAG laser capsulotomy was performed by 1 surgeon in 6 eyes with posterior capsule opacification (PCO) and persistent endotamponade caused by proliferative vitreoretinopathy.
Purpose: To describe a French family with the incomplete type of X-linked congenital stationary night blindness (CSNB2) associated with a novel mutation in the retina-specific calcium channel alpha(1) subunit gene (CACNA1F).
Design: Interventional case report.
Methods: Two family members with a history of nonprogressive night blindness and subnormal visual acuity were clinically examined and the genotype determined by molecular genetic analysis.
Objective: To evaluate the postoperative outcome and complication rate of cataract extraction with implantation of a zonal-progressive multifocal intraocular lens (IOL) for traumatic cataract.
Design: Prospective, nonrandomized, comparative trial.
Participants: Fifty-one eyes of 51 subjects with traumatic cataract caused by nonpenetrating, penetrating, and perforating ocular trauma at two university institutions with more than 12 months follow-up.
Objective: To assess the feasibility of transscleral fixation of a foldable, multifocal intraocular lens (IOL) as an alternative form of optical correction to monofocal IOL implantation in aphakic children and young adults intolerant of contact lenses in the absence of sufficient capsular support.
Study Design: Prospective, nonrandomized, comparative trial.
Participants: Twenty-six eyes of 26 unilateral aphakic patients in the age group 6 to 29 years (mean, 13.
Objective: To evaluate the safety and efficacy of primary phacoemulsification and intraocular lens implantation (PPI) for acute angle-closure glaucoma (ACG).
Study Design: Prospective, nonrandomized comparative trial.
Participants And Intervention: Forty-three eyes of 43 patients with acute ACG and uncontrolled intraocular pressure (IOP) were treated by PPI.
Purpose: To assess the intraocular pressure-lowering efficacy and the postoperative complication profile of viscocanalostomy versus trabeculectomy.
Patients And Methods: Sixty eyes of 60 patients with medically uncontrolled open-angle glaucoma were randomized either to the viscocanalostomy or to the trabeculectomy group of the trial. Viscocanalostomy was performed according to Stegmann's technique using high-molecular-weight sodium hyaluronate to fill the ostia of the Schlemm canal.
Purpose: Epidemiologic studies have shown that various lifestyle characteristics are statistically associated with the chronic open-angle glaucomas. This study was designed to investigate the influence of individual factors on the light-microscopic morphology of the trabecular meshwork in open-angle glaucomas.
Methods: Quantitative computer-assisted topographic analysis of the trabecular meshwork was performed in meridional sections of 80 trabeculectomy specimens from patients with primary open-angle (n = 36), exfoliative (n = 30) and pigment-dispersion (n = 14) glaucoma.
Objective: To assess the efficacy of a new application technique of mitomycin-C to enhance the outcome of filtering surgery in cases of complicated glaucoma.
Design: Randomized clinical trial.
Participants: Fifty consecutive patients scheduled for glaucoma surgery in one large surgical center.
Objectives: To evaluate the effectiveness and risk profile of deep sclerectomy in surgery for refractory congenital glaucoma.
Design: Retrospective non-comparative interventional case series.
Participants And Interventions: Ten eyes of eight consecutive patients underwent deep sclerectomy for refractory congenital glaucoma.
Objective: To assess outcomes and complications of primary trabeculectomies in fellow eyes in a large group of patients. The assumption was that first and fellow eyes undergoing fistulizing surgical procedures behave similarly in the postoperative period.
Design: Retrospective nonrandomized comparative trial (paired eye study).
Laser-grid trabeculectomy in rabbits: an experimental in-vivo study.
Graefes Arch Clin Exp Ophthalmol
February 2002
Background: Laser-grid trabeculectomy (TE) is a modification of micro-TE designed to enhance the intra- and postoperative safety of filtering surgery by creating several small oval fistulas (max. diameter <200 microm) beneath a scleral flap without peripheral iridectomy.
Methods: After dissecting the conjunctiva and a conventional scleral flap, 10 small perforating fistulas were created in five pigmented rabbits in the region of the gray-white border using an erbium:YAG laser with a beveled side-firing 200 microm endoprobe; conventional TE with iridectomy was performed in another five animals.
Objective: To evaluate the benefits of implantation of a zonal-progressive multifocal intraocular lens (IOL) in prepresbyopic patients with unilateral cataract.
Study Design: Prospective, nonrandomized, comparative trial.
Participants: Ninety-five eyes of 95 prepresbyopic patients aged between 14 and 40 years with either multifocal or monofocal IOL implantation at two institutions and with more than 6 months follow-up.