Publications by authors named "Philip Schippers"
Article Synopsis
- New psychoactive substances (NPS) like 1cP-LSD and 4-AcO-DET have become popular recently, but we don’t know much about how they are broken down in our bodies or if they are harmful.
- Scientists studied how these substances are metabolized using human liver samples and zebrafish larvae, discovering different substances created from them.
- They found no harmful effects from 1cP-LSD or 4-AcO-DET in liver cells, but continued research with other cell lines is needed to better understand their effects.
Sample preparation in untargeted metabolomics should allow reproducible extractions of as many molecules as possible. Thus, optimizing sample preparation is crucial. This study compared six different extraction procedures to find the most suitable for extracting zebrafish larvae in the context of an infection model.
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