Publications by authors named "Philip Sabatini"

Article Synopsis
  • The medial temporal lobe (MTL) is crucial for understanding cognitive decline related to neurodegenerative diseases, but the connection between MTL atrophy and specific proteinopathies remains unclear.
  • Researchers developed two deep learning algorithms to quantitatively measure phosphorylated tau (p-tau) and TDP-43 (pTDP-43) pathology in the MTL, focusing on their roles in Alzheimer's disease and LATE.
  • Their study found that quantitative p-tau measures better correlate with structural changes in the MTL compared to semi-quantitative ratings, revealing significant associations with cortical thickness and volume, especially in severe Alzheimer's cases.
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Article Synopsis
  • * Patients with FTD frequently experience language and social disorders related to damage in specific brain regions, depending on whether the left or right temporal lobes are more affected.
  • * A study of two FTD patients with differing subtypes revealed that their distinct rigid belief systems corresponded with specific patterns of brain atrophy, indicating that different forms of FTD may impact belief formation and social behavior differently due to varying vulnerabilities in brain regions.
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Vigil, JN, Sabatini, PL, Hill, LC, Swain, DP, and Branch, JD. Ammonia inhalation does not increase deadlift 1-repetition maximum in college-aged male and female weight lifters. J Strength Cond Res 32(12): 3392-3397, 2018-Ammonia inhalant use by powerlifters and weight lifters is a prevalent practice with little research support for improved performance.

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