Publications by authors named "Philip M Hayes"
Objective: It is unclear whether there are differences in inflammatory gene expression between abdominal and gluteal subcutaneous adipose tissue (SAT), and between black and white women. We therefore tested the hypotheses that SAT inflammatory gene expression is greater in the abdominal compared to the gluteal depot, and SAT inflammatory gene expression is associated with differential insulin sensitivity (S(I) ) in black and white women.
Design And Methods: S(I) (frequently sampled intravenous glucose tolerance test) and abdominal SAT and gluteal SAT gene expression levels of 13 inflammatory genes were measured in normal-weight (BMI 18-25 kg/m²) and obese (BMI >30 kg/m²) black (n = 30) and white (n = 26) South African women.
Article Synopsis
- The study validated an equation predicting mortality in patients undergoing damage control surgery (DCS) using age, lowest pre-operative pH, and lowest core temperature.
- The validation involved analyzing medical records from 73 patients between 1998-2001, finding that the equation correctly identified 8 patients as "unsalvageable," all of whom died, maintaining a 100% positive predictive value.
- The findings suggest that this equation can be a valuable tool for surgical triage in emergencies, helping to prioritize resources effectively.