Publications by authors named "Philip Leslie"
Int J Pharm
December 2014
Article Synopsis
- The study examines the fluidisation and aerosolisation processes in a split capsule dry powder inhaler, specifically using a GSK Rotahaler(®).
- It employs dynamic real-time techniques, like laser diffraction and high-speed imaging, to assess the effects of lactose carrier characteristics on powder fluidisation, entrainment, and de-agglomeration.
- Major findings indicate that the split capsule significantly affects powder emission mechanisms, and there's a strong correlation between powder permeability and aerosolisation efficiency, suggesting that permeability testing could predict drug delivery performance.
