Bacteriuria and antibiotic use during the third wave of COVID-19 intensive care in Sweden.

Background: Urinary tract infections (UTIs) are prevalent among patients carrying indwelling catheters in the intensive care unit (ICU). This study investigates antibiotic use and bacterial colonisation among ICU patients during the third wave of the COVID-19 pandemic, building on our prior discovery of increased colonisation associated with increased cephalosporin use in early COVID-19.

Methods: Longitudinal urine samples from COVID-19 patients ( = 109) with transurethral catheterisation were analysed for bacterial prevalence, further identified via MALDI-TOF.

Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment.

Antibiotics are essential for treating infections and reducing risks during medical interventions. However, many commonly used antibiotics lack the physiochemical properties for an efficient oral administration when treating systemic infection. Instead, we are reliant on intravenous delivery, which presents complications outside of clinical settings.

Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study.

Objectives: High frequency of antimicrobial prescription and the nature of prolonged illness in COVID-19 increases risk for complicated bacteriuria and antibiotic resistance. We investigated risk factors for bacteriuria in the ICU and the correlation between antibiotic treatment and persistent bacteria.

Methods: We conducted a prospective longitudinal study with urine from indwelling catheters of 101 ICU patients from Uppsala University Hospital, Sweden.

Evolutionary Trajectories toward High-Level β-Lactam/β-Lactamase Inhibitor Resistance in the Presence of Multiple β-Lactamases.

β-Lactam antibiotics are the first choice for the treatment of most bacterial infections. However, the increased prevalence of β-lactamases, in particular extended-spectrum β-lactamases, in pathogenic bacteria has severely limited the possibility of using β-lactam treatments. Combining β-lactam antibiotics with β-lactamase inhibitors can restore treatment efficacy by negating the effect of the β-lactamase and has become increasingly important against infections caused by β-lactamase-producing strains.

Molecular Characterization of Multidrug-Resistant From Foodborne Outbreaks in Sweden.

The foodborne pathogen causes gastrointestinal infections worldwide. In the spring of 2019, the Swedish Public Health Agency and Statens Serum Institut in Denmark independently identified an outbreak caused by 4/O:3 that after sequence comparison turned out to be a cross-border outbreak. A trace-back investigation suggested shipments of fresh prewashed spinach from Italy as a common source for the outbreak.

Complete Genome Assembly of Multidrug-Resistant Yersinia enterocolitica Y72, Isolated in Sweden.

Here, we report the complete genome sequence of a Swedish clinical strain of , Y72. With emerging outbreaks circulating in Nordic countries, the Y72 genome will provide more insights on the genetic relatedness and antibiotic resistance dissemination in future studies.

Admicellar polymerization of methyl methacrylate on aluminum pigments.

Micrometer-sized aluminum particles used as pigments in silver inks and coatings are reactive in water-based formulations. This leads to hydrogen gas evolution in the paint containers and loss of the silvery appearance of the coating. The protection of aluminum pigments from water is called inhibition and it was shown in earlier work that anionic surfactants of the phosphate ester type are effective as inhibitors, forming a protective bilayer on the aluminum pigment surface.

Adsorption of sodium dodecyl sulfate and sodium dodecyl phosphate on aluminum, studied by QCM-D, XPS, and AAS.

The adsorption of two anionic surfactants, sodium dodecyl sulfate (SDS) and sodium dodecyl phosphate (SDP), at surfaces of aluminum and aluminum oxide has been studied by means of atomic absorption spectrometry (AAS), X-ray photoelectron spectroscopy (XPS), and quartz crystal microbalance with dissipation monitoring (QCM-D). It was shown that more SDP than SDS binds to the surface and that SDP prevents dissolution of aluminum in water whereas SDS does not. This was not obvious, since the adsorption isotherms of the two surfactants to aluminum pigment powder are quite similar, as shown in an earlier work.

Surface modification for aluminium pigment inhibition.

This review concerns surface treatment of aluminium pigments for use in water borne coatings. Aluminium pigments are commonly used in coatings to give a silvery and shiny lustre to the substrate. Such paints and inks have traditionally been solvent borne, since aluminium pigment particles react with water.