- The case study presents a 74-year-old man with severe essential tremor and diffuse skull thickening (hyperostosis), who did not improve after undergoing magnetic resonance-guided focused ultrasound (MRgFUS) treatment.
- Pre-treatment imaging indicated a low skull density ratio (SDR) and the presence of tricortical hyperostosis, yet post-treatment MRI showed no changes or lesions.
- A literature review revealed that out of three similar cases of patients with hyperostosis, all also failed MRgFUS treatment, suggesting that tricortical hyperostosis may be a contraindication for this therapeutic approach.