Publications by authors named "Philip Haigh"
Context: Primary hyperparathyroidism (PHPT) has initially been implicated in adverse maternal and neonatal outcomes, while subsequent population studies have failed to show an association.
Objective: To compare maternal, pregnancy, and neonatal outcomes in patients with and without PHPT.
Design: Retrospective matched-cohort study (2005-2020).
Importance: Limited evidence supports kidney dysfunction as an indication for parathyroidectomy in asymptomatic primary hyperparathyroidism (PHPT).
Objective: To investigate the natural history of kidney function in PHPT and whether parathyroidectomy alters renal outcomes.
Design: Matched control study.
Background: Nephrolithiasis is a classic indication for parathyroidectomy in primary hyperparathyroidism patients; however, the effects of parathyroidectomy on nephrolithiasis recurrence are not well studied. The aim was to determine effect of parathyroidectomy on time to first nephrolithiasis recurrence and recurrence rate per patient-years.
Methods: A retrospective cohort study of patients diagnosed with primary hyperparathyroidism and at least one episode of nephrolithiasis was performed.
Background: Parathyroidectomy (PTX) increases bone mineral density and decreases fracture risk in patients with primary hyperparathyroidism. This study examined the effect of adding bisphosphonates either before or after PTX on skeletal outcomes.
Methods: A retrospective cohort study of bisphosphonate-naïve patients (1995-2016) with osteoporosis and primary hyperparathyroidism (calcium >10.
Context: Total thyroidectomy has been shown to provide a cost-effective and efficient method of permanently treating Graves disease; however, hypocalcemia can be a common complication.
Objective: To evaluate the risk of hypocalcemia after total thyroidectomy in patients with vs without Graves disease.
Design: The 2016 American College of Surgeons National Surgical Quality Improvement Program participant use data files for procedure-targeted thyroidectomy and from 5871 patients were merged.
The natural biochemical history of untreated primary hyperparathyroidism (PHPT) is poorly understood. The purpose of this study was to determine the extent of biochemical fluctuations in patients with PHPT. Retrospective cohort study from January 1, 1995, to December 31, 2014.
View Article and Find Full Text PDFBackground: Patients with primary hyperparathyroidism are at risk for skeletal and renal end-organ damage.
Methods: We studied patients with biochemically confirmed primary hyperparathyroidism from 1995-2014 and quantified the frequency of osteoporosis, nephrolithiasis, hypercalciuria, and decrease in renal function.
Results: The cohort comprised 9,485 patients.
Background: Parathyroidectomy improves bone mineral density and decreases risk for fracture in patients with primary hyperparathyroidism. The aim of this study was to determine skeletal consequences of failed parathyroidectomy.
Methods: A retrospective, cohort study of patients with biochemically confirmed primary hyperparathyroidism within a vertically integrated health system was performed (1995-2014).
Context: Endocrine and exocrine insufficiency after partial pancreatectomy affect quality of life, cardiovascular health, and nutritional status. However, their incidence and predictors are unknown.
Objective: To identify the incidence and predictors of new-onset diabetes and exocrine insufficiency after partial pancreatectomy.
Background: It has been observed that negative sestamibi scans may impact practice patterns in patients with primary hyperparathyroidism. However, there are no published data on the issue. The objective was to elucidate the influence of negative sestamibi scans on referrals by endocrinologists for parathyroidectomy and surgeon decision-making.
View Article and Find Full Text PDFContext: The oncologic benefit of prophylactic central lymph node dissection (pCLND) in node-negative papillary thyroid cancer has been debated.
Objective: To determine the use of pCLND in an integrated health care system and to evaluate recurrence in the cohort.
Design: Retrospective cohort study of patients with clinically node-negative papillary thyroid cancer who underwent total thyroidectomy with or without pCLND in Kaiser Permanente Southern California Region hospitals between January 1996 and December 2008.
Background: The comparative effectiveness of surgical and medical treatments on fracture risk in primary hyperparathyroidism (PHPT) is unknown.
Objective: To measure the relationship of parathyroidectomy and bisphosphonates with skeletal outcomes in patients with PHPT.
Design: Retrospective cohort study.
Background: The risk of hypothyroidism after hemithyroidectomy is variable, and most estimates come from single institutional studies. The purpose of the present study was to determine the incidence of hypothyroidism at the population level, and to evaluate predictive factors for hypothyroidism after hemithyroidectomy.
Methods: This retrospective study identified euthyroid patients who underwent hemithyroidectomy between 2000 and 2010 for benign disease in Kaiser Permanente Southern California regional hospitals.
Importance: Current guidelines recommend that patients with an initial episode of gallstone pancreatitis receive cholecystectomy. However, for various reasons, many patients do not.
Objective: To determine the risk of developing recurrent gallstone pancreatitis in patients who never receive a cholecystectomy.
Context: The epidemiology of primary hyperparathyroidism (PHPT) has generally been studied in Caucasian populations.
Objective: The aim was to examine the incidence and prevalence of PHPT within a racially mixed population.
Design: A descriptive epidemiologic study was performed.
Article Synopsis
- The study investigates the prevalence of non-inguinal abdominal wall hernias and their association with body mass index (BMI) and other demographic factors among over 2.8 million patients treated at 14 hospitals.
- Findings reveal that 0.9% of patients had specified hernias, with a higher occurrence in individuals aged over 50 and those with higher BMI, particularly those above 60 kg/m2, showing a strong correlation with hernia development and incarceration risk.
- The data also indicates that male gender is associated with a higher risk of hernias, while female gender is linked to a lower risk, highlighting the importance of age and BMI in hernia risk assessments.
Objective: To determine parathyroidectomy (PTx) rates in patients who satisfy the consensus guidelines for surgical treatment of primary hyperparathyroidism (PHPT).
Background: Surgery for PHPT is recommended for all symptomatic patients and select asymptomatic patients meeting established consensus criteria. Adherence to the consensus guidelines has not been examined systematically, because of inadequate information regarding patients managed nonoperatively.
Objective: The aim of this study was to determine the morbidity of a defunctioning loop ileostomy and the subsequent closure rate, and to identify the predictors of complications and nonclosure of stoma.
Design: This study is a retrospective review of a single-institution experience.
Patients: All patients who underwent a planned temporary defunctioning loop ileostomy performed synchronously with a pelvic anastomosis during a 6-year period were included.
Background: Systematic study of outcomes of initial surgery for primary hyperparathyroidism (PHPT) has been limited by selection and self-reporting biases. To avoid these biases, we evaluated parathyroidectomy (PTx) outcomes within an integrated health care system encompassing 3.25 million enrollees.
View Article and Find Full Text PDFObjectives: To review our experience with patients treated for anal fistula secondary to cryptoglandular disease and to determine factors that influence postoperative outcome.
Design: Retrospective review.
Setting: A regional tertiary referral center.
Extent of thyroidectomy and survival in the SEER database: a case of citation amnesia.
Arch Otolaryngol Head Neck Surg
August 2011
Background: Single-institution case series suggest that elderly patients do as well as younger patients after pancreaticoduodenectomy.
Objectives: To compare morbidity and mortality after pancreaticoduodenectomy in patients older than 70 years vs younger patients.
Hypothesis: Elderly patients have worse 30-day outcomes.
Should barium enema be the next step following an incomplete colonoscopy?
Int J Colorectal Dis
November 2010
Introduction: Double contrast barium enema (DCBE) is used to screen and diagnose colorectal disease and is often recommended following an incomplete colonoscopy. The purpose of this study was to determine the value of DCBE following an incomplete colonoscopy.
Materials And Methods: A retrospective review was conducted of all patients who had an incomplete colonoscopy at Kaiser Permanente, Los Angeles in a 6-year period.