Publications by authors named "Philip G Holtzapple"
Inflamm Bowel Dis
December 2012
Article Synopsis
- Cytokine signaling pathways are crucial in the development of inflammatory bowel disease (IBD), affecting conditions like ulcerative colitis (UC) and Crohn's disease (CD) with distinct and overlapping features.
- The study involved analyzing 70 immune-related genes in colon biopsy samples from UC and CD patients, using an advanced gene quantification technique.
- Results showed different regulation of immune signaling molecules between UC and CD, as well as between active and quiescent states, highlighting potential novel biomarkers for diagnosing and monitoring IBD.
