Publications by authors named "Philip D Knollman"

Objectives: To compare the demographic and clinical characteristics of children with Down syndrome who did and did not receive polysomnography to evaluate for obstructive sleep apnea after publication of the American Academy of Pediatrics' guidelines recommending universal screening by age 4 years.

Study Design: Retrospective cohort study.

Setting: Single tertiary pediatric hospital.

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Article Synopsis
  • The study aimed to compare the rates and ages of children with Down syndrome (DS) undergoing sleep studies (PSG) for obstructive sleep apnea (OSA) before and after new pediatric guidelines were introduced in 2007.
  • A total of 766 children with DS were analyzed; while the overall percentage receiving PSG remained similar (around 60%), the mean age at which children had their first PSG decreased significantly from 5.3 years to 3.4 years after the guidelines were introduced.
  • Despite the earlier screening age, the rates of OSA detected remained consistent between the pre- and post-guideline groups, with 79.8% and 75.9% respectively.*
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Pediatric hyperthyroidism can be multifactorial, with Graves' disease (GD) being the most common etiology. Treatment focuses on identification of the cause of the hyperthyroidism and achieving a biochemical cure with symptom resolution. This article highlights the clinical presentation, diagnosis, and treatment of a pediatric patient with GD.

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Purpose Of Review: Pediatric tracheotomy is a common procedure. Given the risk of morbidity and mortality associated with long-term placement, it is imperative that decannulation is considered once the indication for tracheotomy placement is corrected or resolved. In this article, we discuss the critical steps necessary for the assessment of readiness for decannulation, and we review the recent literature that supports several methods of evaluation that may be incorporated into a protocol for decannulation.

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