Publications by authors named "Philip Croon"

Medical datasets are vital for advancing Artificial Intelligence (AI) in healthcare. Yet biases in these datasets on which deep-learning models are trained can compromise reliability. This study investigates biases stemming from dataset-creation practices.

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Unlabelled: Atrial fibrillation (AF) is a prevalent and clinically significant cardiac arrhythmia, with a growing incidence. The primary objectives in AF management are symptom relief, stroke risk reduction, and prevention of tachycardia-induced cardiomyopathy. Two key strategies for rhythm control include antiarrhythmic drug therapy and pulmonary vein isolation (PVI), with PVI being recommended for selected patients.

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Article Synopsis
  • The study focused on identifying imaging biomarkers for pre-clinical cardiomyopathy in healthy people with genetic variants linked to hypertrophic cardiomyopathy (HCM) or dilated cardiomyopathy (DCM).
  • Out of 40,169 participants, 13 cardiac magnetic resonance (CMR) measurements were found to be linked to atrial fibrillation (AF) and 15 with heart failure (HF), with specific measurements correlating differently with HCM and DCM genetic risk.
  • The findings suggest that certain CMR measurements, particularly from the right side of the heart, can indicate early changes in heart function in individuals with HCM genetic variants, while left ventricular measures relate to DCM genetic risks
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The number of inherited heart disease (IHD) studies using artificial intelligence (AI) has increased rapidly over the last years. In this scoping review, we aimed to present an overview of the current literature available on the applicability of AI within the field of IHD. The literature search resulted in eighteen articles in which an AI model was trained and tested, mostly for diagnostic and predictive purposes.

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Objective: Cerebral perfusion analysis based on arterial spin labeling (ASL) MRI has been proposed as an alternative to FDG-PET in patients with neurodegenerative disease. Z-maps show normal distribution values relating an image to a database of controls. They are routinely used for FDG-PET to demonstrate disease-specific patterns of hypometabolism at the individual level.

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