Governing in the Anthropocene: are there cyber-systemic antidotes to the malaise of modern governance?

Abstract: The Anthropocene imposes new challenges for governments, demanding capabilities for dealing with complexity and uncertainty. In this paper we examine how effective governing of social-biophysical dynamics is constrained by current processes and systems of government. Framing choices and structural determinants combine to create governance deficits in multiple domains, particularly in relation to the governing of complex larger-scale social-biophysical systems.

Defining a Central Monitoring Capability: Sharing the Experience of TransCelerate BioPharma's Approach, Part 2.

Background: TransCelerate's model approach to risk-based monitoring (RBM) includes the application of the appropriate monitoring activities to enable both the early detection and timely resolution of issues. This article is a follow-up to part 1, published in the September 2014 issue with the same title.

Methods: The intent of this paper is to share information on what has been learned by various companies' applications of central monitoring activities based on different RBM operating models.