Publications by authors named "Phelisa Sogayise"
Int J Nephrol
October 2020
Article Synopsis
- Lupus nephritis (LN) can lead to severe complications like kidney failure and death, with limited comparative data on treatment efficacy between mycophenolate mofetil (MMF) and intravenous cyclophosphamide (IVCYC) in African populations.
- A retrospective study in Cape Town analyzed 84 patients with biopsy-confirmed proliferative LN, finding no significant differences in remission or relapse rates after treatment with MMF or IVCYC, although baseline kidney function predicted mortality risk.
- The research indicates that both induction therapies yield comparable outcomes for patients in South Africa, but emphasizes the need for a prospective, randomized study for a more thorough evaluation of these treatments.
