Publications by authors named "Phei San Lai"
Article Synopsis
- - Conventional cancer treatments like chemotherapy often cause significant side effects and can make the immune system less effective against tumors, making it harder to develop targeted immunotherapies.
- - This study focuses on a new method using a hapten-based pre-immunization strategy to generate antibodies specifically targeting cancer cells expressing the TrkC receptor, enhancing immune response without affecting normal cells.
- - Results showed that the dipeptide-hapten construct (IYIY-DNP) significantly reduced tumor growth in DNP-immunized mice with tumors expressing TrkC, demonstrating its potential as an effective immunotherapy approach for targeting specific cancer types.