Publications by authors named "Phebee Gouinguenet"
Article Synopsis
- - The Mediterranean diet (MedDiet) is linked to a lower risk of several non-communicable diseases, potentially through its effects on gut microbiota composition and metabolism.
- - A systematic review of 34 studies (17 randomized controlled trials and 17 observational studies) found no consistent evidence that the MedDiet significantly alters gut microbiota or its metabolites.
- - Variations in study methods, cohort characteristics, and the quality of research may explain the lack of clear results, highlighting the need for more structured studies to better understand the MedDiet's impact on gut health.
Background: Copy number (CN) variation (CNV) of the salivary amylase gene (AMY1) influences the ability to digest starch and may influence glucose homeostasis, obesity and gut microbiota composition. Hence, the aim was to examine the association of AMY1 CNV with fasting glucose, BMI, and gut microbiota composition considering habitual starch intake and to investigate the effect of AMY1 CNV on the postprandial response after two different starch doses.
Methods: The Malmö Offspring Study (n = 1764, 18-71 years) was used to assess interaction effects between AMY1 CNV (genotyped by digital droplet polymerase chain reaction) and starch intake (assessed by 4-day food records) on fasting glucose, BMI, and 64 gut bacteria (16S rRNA sequencing).