Antibiotic-loaded hydroxyapatite scaffolds fabricated from bones for orthopaedics.

This work aimed to develop new antibiotic-coated/ antibiotic-loaded hydroxyapatite (HAp) scaffolds for orthopaedic trauma, specifically to treat the infection after fixation of skeletal fracture. The HAp scaffolds were fabricated from the Nile tilapia ( bones and fully characterized. The HAp scaffolds were coated with 12 formulations of poly (lactic--glycolic acid) (PLGA) or poly (lactic acid) (PLA), blended with vancomycin.

sp. nov., an endophytic actinomycete isolated from the root of (L.).

An endophytic actinobacterium, designated strain CA1R205, was isolated from the surface-sterilized root of L. collected from Ratchaburi province, Thailand. The taxonomic position of this strain was evaluated using a polyphasic approach.