Publications by authors named "Phatcharaporn Thongwatchara"
Article Synopsis
- Cholangiocarcinoma (CCA) patients in Southern Thailand exhibit late-stage diagnoses, with 59.4% diagnosed at TMN stage IV, and the overall median survival is only 5-6 months.
- The study reviewed 223 CCA patients between 2018 and 2021, identifying that intrahepatic CCA (iCCA) was the most common subtype (49.3%), and only 15.1% of patients were considered resectable.
- Key factors affecting survival included TMN stage, with a higher risk of mortality linked to late-stage diagnosis, while systemic chemotherapy and palliative biliary drainage improved outcomes for unresectable patients.
Background: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutations have been reported in many cancers, including head and neck squamous cell carcinoma (HNSCC). The frequency of these mutations varies among tumor locations and might be relevant to treatment outcomes among HNSCC. In this study, we examined the frequency of PIK3CA mutations in the different subsites of HNSCC.
View Article and Find Full Text PDFAxillary lymph node (ALN) metastasis is a key step of tumor progression in breast cancer and is associated with an unfavorable prognosis. However, the mechanisms of this process are not well understood. Proteomic technologies have led to identification of specific protein markers and a better understanding of the cellular processes.
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