Dosimetric Performance of Poly(vinyl alcohol)/Silver Nanoparticles Hybrid Nanomaterials for Colorimetric Sensing of Gamma Radiation.

A colorimetric liquid sensor based on a poly(vinyl alcohol)/silver nanoparticle (PVA/AgNPs) hybrid nanomaterial was developed for gamma radiation in the range of 0−100 Gy. In this study, gamma rays (Cobalt-60 source) triggered the aggregation of AgNPs in a PVA/silver nitrate (AgNO3) hybrid solution. The color of this solution visibly changed from colorless to dark yellow.

A deep learning model (FociRad) for automated detection of γ-H2AX foci and radiation dose estimation.

DNA double-strand breaks (DSBs) are the most lethal form of damage to cells from irradiation. γ-H2AX (phosphorylated form of H2AX histone variant) has become one of the most reliable and sensitive biomarkers of DNA DSBs. However, the γ-H2AX foci assay still has limitations in the time consumed for manual scoring and possible variability between scorers.