Publications by authors named "Pharuhas Chanprapaph"

Objectives: To evaluate the efficacy of postpartum tubal sterilization training program with minilaparotomy approach (PTSMA).

Study Design: From September 2020 to November 2021, 24 first-year Obstetrics and Gynecology (Ob/Gyn) residents were randomly allocated into 2 groups of traditional apprenticeship learning (watching video clip) versus apprenticeship learning plus PTSMA attending. The program consisted of didactics followed by self-practicing with 2 stations of postpartum tubal sterilization simulators (PTSS).

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The "placental bulge" sign (focal area of myometrial-placental bulging beyond the normal uterine contour) on ultrasound (US) or MRI is postulated to represent deeper venous invasion in placenta accreta spectrum (PAS) disorder and may represent severe PAS. The purpose of this study was to evaluate the diagnostic performance and interobserver agreement of US and MRI features for diagnosis of severe PAS, with an emphasis on the placental bulge sign. This retrospective study included 62 pregnant women (mean age, 33.

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Article Synopsis
  • The study compared maternal and neonatal outcomes between elective caesarean section (ElCS) and emergency caesarean section (EmCS) for singleton-term breech presentations at Siriraj Hospital from 2007-2015, involving 2,178 women.
  • Both groups showed no maternal or neonatal deaths, but EmCS was associated with a longer hospital stay and a significantly lower one-minute Apgar score.
  • No significant differences in serious complications were found between ElCS and EmCS, indicating that EmCS can be performed without higher risks in this specific situation.
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Purpose: To determine bone mineral density (BMD) at the age of peak bone mass in women who previously experienced pregnancy and breastfeeding during adolescence.

Materials And Methods: In this retrospective study, female volunteers aged 24-30 years who were pregnant during the age of 15-19 years and have had one to two babies were recruited. All of them experienced breastfeeding without history of bone- or calcium-related problems, such as fracture or low calcium intake.

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Objective: To establish nomograms for fetal atrioventricular (AV) time intervals assessed by 3 different pulsed-wave Doppler techniques: left ventricular inflow and outflow tracts (LV in/out), superior vena cava and ascending aorta (SVC/AA), and pulmonary artery and pulmonary vein (PA/PV).

Methods: A cross-sectional study was performed in 311 normal fetuses divided into 5 groups between 16 and 38 weeks. Pulsed-wave Doppler-derived AV intervals were measured by interrogation of flow in LV in/out, SVC/AA, and PA/PV.

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Article Synopsis
  • Lactation can cause site-specific bone loss in breastfeeding mothers, observed in lumbar vertebrae during mid-lactation and femoral bone in late lactation.
  • Serum calcium levels dropped below normal by late lactation, and a strong correlation was found between the bone turnover marker P1NP and femoral bone density.
  • Early calcium supplementation before mid-lactation is advised to prevent bone loss, with P1NP being the most reliable marker for predicting this loss.
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Background: Multiple first trimester aneuploidy sonomarkers have been introduced recently.

Objective: To evaluate the efficacy of first trimester sonomarkers in fetal aneuploidy detection without serum markers.

Methods: There were entirely 280 fetuses with 11-13+6 weeks' gestation (crown-rump -length between 45-84 mm) enrolled to assess nuchal translucency thickness (NT), nasal bone (NB), tricuspid regurgitation (TR) and ductus venosus (DV) flow.

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  • * Data were collected from 3307 women with singleton pregnancies who underwent the procedure between 2007 and 2012, revealing a very low total pregnancy loss rate of 0.2% within 4 weeks post-testing.
  • * Advanced maternal age was the primary reason for amniocentesis, and the study identified various risk factors for fetal loss, making it important for patient counseling prior to the procedure.
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Background: Numerous factors, both in the mother and in the infant, are involved in achieving breastfeeding. One maternal factor is normality of the nipples. However, no definition of normal nipple length or width or normal range and changes in pregnant women exists.

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Objective: The benefit of antenatal nipple correction remains inconclusive. This study aims to demonstrate the value of breast cups in lengthening of short nipples and to compare the breastfeeding rate between the users and the nonusers.

Subjects And Methods: Singleton pregnant women with at least one short nipple (<7.

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Aims: To establish the normative data distribution of nuchal translucency (NT) thickness in Thai fetuses.

Methods: A cross-sectional multicenter study was conducted among 6,455 women with singleton pregnancies and gestational age between 10 and 14 weeks. For each case, the fetal crown-rump length (CRL) and NT were measured by transabdominal ultrasound.

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Objective: To determine the correlation between the rapid biophysical profile (rBPP), the combination of amniotic fluid index (AFI), and sound-provoked fetal movement (SPFM) detected by ultrasound, and the full biophysical profile (FBP) in terms of abnormal and normal result.

Material And Method: A prospective study was performed in 200 singleton pregnancies with no fetal anomalies between 30-42 weeks of gestation indicated for non-stress test (NST). All participants received both the standard (FBP) and the new rBPP examinations.

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Objective: To determine the correlation between actual birthweight (BW) and fetal weight calculated from fractional thigh volume (ThiV).

Material And Method: The authors have conducted a prospective, cross-sectional study of normal Thai fetal thigh volume. There were 176 eligible pregnant women who met the criteria of singleton with no fetal anomaly were recruited into the present study.

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Objective: To assess the specificity of tricuspid regurgitation (TR) in prediction of Down syndrome in Thai fetuses at 17-23 weeks' gestation and to determine the prevalence of TR among normal chromosome fetuses in a high-risk population.

Material And Method: A prospective study was performed in 395 high-risk pregnant women who underwent amniocentesis or cordocentesis for fetal karyotyping at 17-23 weeks. The presence or absence of TR was determined by pulsed wave Doppler at the time of prenatal diagnosis.

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Article Synopsis
  • A severe case of twin-twin transfusion syndrome (TTTS) at 17 weeks led to a successful fetoscopic laser ablation procedure, but the recipient fetus died shortly after.
  • After pregnancy termination, the donor fetus appeared unusually plethoric while the recipient was pale, indicating a case of reverse TTTS.
  • The study revealed a remaining deep vein-vein anastomosis, highlighting the challenges of current placental surgery techniques, marking this as the first confirmed instance of reverse TTTS causing fetal loss post-laser photocoagulation.
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Four fetuses were diagnosed antenatally with double outlet of right ventricle (DORV) at 17, 20, 26, and 28 weeks' gestation, respectively, using 2-dimensional sonography. Chromosome study was normal in all 4 cases, and there were no extracardiac abnormalities. The sonographic diagnoses were based on the following findings: (1) arising of the 2 great vessels predominantly from the right ventricle; (2) the presence of bilateral coni; and (3) parallel direction of the 2 vessels rather than the normal perpendicular course.

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  • The study compares manual fetal stimulation (MST) to the standard nonstress test (NST) in high-risk pregnancies.
  • It involved 540 participants, split evenly between the two methods, with analysis conducted on fetal heart rate data.
  • Results showed MST had a higher reactivity rate (98.9% vs. 84.4%) and required less testing time (about 8 minutes vs. about 14 minutes), indicating MST's effectiveness and efficiency in monitoring fetal health.
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Hemoglobin Constant Spring (Hb CS) is an unstable hemoglobin (Hb) variant that results from a nucleotide substitution at the termination codon of the alpha2-globin gene. The compound heterozygosity of alpha-thalassemia and Hb CS (--/alphaCSalpha) results in a Hb H/CS disease which is clinically more severe than deletional Hb H disease. Homozygosity of Hb CS (alphaCSalpha/alphaCSalpha) is generally characterized with mild hemolytic anemia, jaundice, and splenomegaly.

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The objective of this report was to emphasize the sonographic findings of tetralogy of Fallot (TOF) during the prenatal period. Four fetuses with TOF were prenatally diagnosed at gestational ages of 25, 28, 25, and 32 weeks. Based on this small series, prenatal sonographic findings suggestive of TOF may be summarized as follows: (1) a large aortic root, which is the most common prenatal sonographic finding, (2) a small pulmonary artery or stenosis of the right ventricular outflow tract, (3) a ventricular septal defect in the outlet portion of the septum, (4) an overriding aorta, which is best seen in the long-axis view, and (5) right ventricular hypertrophy.

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Objectives: To evaluate intra- and inter-observer variations of nuchal translucency (NT) measurements and study the duration of measurements.

Subjects: One hundred and forty-seven singleton pregnant women with 10-14 weeks of gestation who had attended antenatal clinic during January 1st, 2000-August 31st, 2001 were included.

Methods: Crown-rump length and NT were measured three times for each woman.

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Objective: To describe the experience of the first 50 cases of cordocentesis after practicing with cordocentesis model.

Material And Method: Cordocentesis model consisted of a water-filled transparent glass box covered with a rubber latex sheet with or without piece of pork skin. A 30-cm umbilical cord filled with mercurochrome, hung inside the container, was the target for the puncture.

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Objective: To evaluate the incidence and volume of feto-maternal hemorrhage following cordocentesis.

Study Design: Descriptive study.

Material And Method: One hundred and sixteen asymptomatic non-anemic pregnant women with an indication for cordocentesis at 18-22 weeks of gestation between January and June 2004 were recruited.

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Article Synopsis
  • Ductus arteriosus aneurysm is a rare condition observed in fetuses, which was diagnosed in a 35-year-old woman's baby during a 30-week ultrasound due to abnormal fetal heart and blood flow patterns.
  • Upon diagnosis, the mother experienced preterm labor and received medications (dexamethasone and terbutaline) to manage the situation.
  • Unfortunately, shortly after starting terbutaline, the fetal heart rate dropped significantly, suggesting severe complications possibly linked to the treatments.
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Ebstein anomaly, an abnormally low insertion of the tricuspid valve, occurs in 0.5% of patients with congenital heart disease. In rare cases, this disorder may be complicated by congestive heart failure in utero and hydrops fetalis.

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  • The study aimed to assess the prevalence of gestational diabetes mellitus (GDM) among pregnant women screened with the glucose challenge test (GCT) at Maharaj Nakorn Chiang Mai Hospital from October 2001 to December 2002.
  • Out of 1000 pregnant women, 411 underwent GCT testing, revealing a 7.05% prevalence of GDM, with specific risk factors including advanced maternal age and family history of diabetes.
  • The study highlighted the sensitivity and low predictive value of GCT, along with various pregnancy outcomes, emphasizing the need for selective screening in high-risk pregnancies.
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