Extended-spectrum beta-lactamase-producing and : insights from a tertiary hospital in Southern Thailand.

Unlabelled: Broad-spectrum ampicillin-resistant and third-generation cephalosporin-resistant Enterobacteriaceae, particularly and that have pathological features in humans, have become a global concern. This study aimed to investigate the prevalence, antimicrobial susceptibility, and molecular genetic features of extended-spectrum beta-lactamase (ESBL)-producing and isolates in Southern Thailand. Between January and August 2021, samples ( = 199) were collected from a tertiary care hospital in Southern Thailand.

Genome Sequence of a Clostridioides difficile Strain Isolated from Feces from a Patient in Southern Thailand.

Clostridioides difficile is a Gram-positive, obligate anaerobic, toxin-producing bacillus that is linked to antibiotic-associated diarrhea. Here, we report the whole-genome sequence of a C. difficile strain isolated from stool from a patient, using next-generation sequencing (MGISEG-2000).

Antimicrobial Susceptibility and Molecular Features of Colonizing Isolates of and the Report of a Novel Sequence Type (ST) 3910 from Thailand.

is an important pathogen as it can cause hospital-acquired infections. Additionally, it can also colonize in patients and in other various environments. Hence, this study aimed to investigate the antimicrobial susceptibility, and to study the molecular features, of colonizing isolates of from Songklanagarind Hospital, Thailand.

Characterization of probiotic properties and development of banana powder enriched with freeze-dried probiotics.

is one of the probiotic bacteria widely identified from fermented foods. The application of is commonly used in dairy and non-dairy products. To investigate the probiotic properties of cells including their acid, pepsin, pancreatin, and bile salt tolerances; adhesion ability; antipathogen activity; and antibiotic susceptibility, cells were incorporated into skim milk and lyophilized by freeze drying.

Prevalence of carbapenemase genes among multidrug-resistant isolates from tertiary care centers in Southern Thailand.

Objectives: To assess the prevalence of carbapenemase genes among multidrug-resistant () isolates from tertiary care centers in Southern Thailand.

Methods: The prevalence of carbapenemase genes in isolates collected from patients hospitalized between 2015-2017 in 2 tertiary care hospitals in Songkhla Province, Southern Thailand, was investigated. Standard laboratory procedures were followed and disk diffusion test was used for bacterial identification and susceptibility evaluations.

Prevalence and characterization of extended-spectrum β-lactamase-producing and isolated from raw vegetables retailed in Southern Thailand.

Background: The increasing prevalence of broad-spectrum ampicillin-resistant and third-generation cephalosporin-resistant , particularly and , has become a global concern, with its clinical impacts on both human and veterinary medicine. This study examined the prevalence, antimicrobial susceptibility, and molecular genetic features of extended-spectrum β-lactamase (ESBL)-producing and isolates from 10 types of raw vegetables.

Methods: In total, 305 samples were collected from 9 markets in Nakhon Si Thammarat, Thailand, in 2020.

Molecular epidemiology of vancomycin-resistant clinical isolates in a tertiary care hospital in southern Thailand: a retrospective study.

Objective: Vancomycin-resistant enterococci are nosocomial pathogens that are responsible for commonly causing healthcare-associated infections, and they exhibit increased resistance to many antimicrobials, particularly to vancomycin. The epidemiological data available on vancomycin-resistant enterococci (VRE) in Thailand are inadequate.

Methods: Using enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR), this study investigated genes that encode antimicrobial resistance and genetic relatedness to further understand VRE prevalence.

Probiotic Properties of Lactobacillus Species Isolated from Fermented Palm Sap in Thailand.

Lactic acid bacteria (LAB), which are the most frequently used probiotics in foods, confer health benefits such as antimicrobial activity, immune stimulation, and anticancer activity. Fermented palm sap is a potential source of LAB. This study aimed to evaluate in vitro antimicrobial and probiotic properties of LAB isolated from traditional fermented palm sap in Thailand.

Isolated From Infant Feces Inhibits Toxigenic .

infection is implicated as a major cause of antibiotic-associated diarrhea in hospitals worldwide. Probiotics, especially lactic acid bacteria, are the most frequently used alternative treatment. This study aims to identify potential probiotic enterococci strains that act against strains and exert a protective effect on colon adenocarcinoma cells (HT-29 cells).

METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS FROM READY-TO-EAT FOODS IN A HOSPITAL CANTEEN, SOUTHERN THAILAND: VIRULENCE CHARACTERIZATION AND GENETIC RELATIONSHIP.

Due to the existence of sporadic cases caused by methicillin-resistant Staphylococcus aureus (MRSA) in Songklanagarind Hospital, Songkhla, southern Thailand where a canteen is located in close vicinity, this study investigated the presence of MRSA, including mecA-carrying S. aureus (MCSA), contamination in 105 ready-to-eat (RTE) food samples sold in this canteen. Coagulase-negative MRSA (MR-CoN) and coagulase-negative MCSA (MCSA-CoN) contaminations were observed in various RTE foods with unriped-papaya salad having significantly highest incidence of MCSA-CoN contamination (p < 0.

Molecular characterization and relationship of methicillin-resistant Staphylococcus aureus among strains from healthy carriers and university hospital patients, southern Thailand.

Methicillin-resistant Staphylococcus aureus (MRSA) plays an important role in nosocomial infections including those in communities. MRSA enables colonization in the nares and throats of healthy people. In this study, investigation of MRSA prevalence from the throats of healthy subjects in southern Thailand revealed that among 153 isolates, 2 showed mecA+ genotype by PCR.

Comparative study of pharmacokinetics/ pharmacodynamics of ciprofloxacin between 400 mg intravenously every 8 h and 400 mg intravenously every 12 h in patients with gram negative bacilli bacteremia.

Objective: To compare the ratio of the area under the concentration-time curve at 24 hours to the minimum inhibitory concentration value (24-h AUC/MIC) of ciprofloxacin between 400 mg intravenously every 8 h and 400 mg intravenously every 12 h.

Material And Method: A prospective, randomized, two-way crossover study of 10 patients with gram-negative bacilli bacteremia was conducted. All patients were randomized to receive ciprofloxacin in both regimens consecutively: (i) 400 mg intravenously every 8 h for four doses; (ii) 400 mg intravenously every 12 h for four doses.

Comparison of continuous infusion versus intermittent infusion of vancomycin in patients with methicillin-resistant Staphylococcus aureus.

Objective: To compare the pharmacokinetics of vancomycin administration by continuous infusion and intermittent infusion.

Material And Method: A prospective, randomized, two-way crossover study of 12 patients with methicillin-resistant Staphylococcus aureus infections was conducted. All patients were randomized to receive vancomycin in both regimens consecutively: (i) infusion of 15 mg/kg of vancomycin as a loading dose for 1 h followed by 30 mg/kg of vancomycin as a continuous infusion over 24 h for 48 h; and (ii) intermittent infusion of 15 mg/kg of vancomycin for 1 h every 12 h for 48 h.