Publications by authors named "Phan Huu Phuc"

Over the past 15 years, and despite many difficulties, significant progress has been made to advance child and adolescent tuberculosis (TB) care. Despite increasing availability of safe and effective treatment and prevention options, TB remains a global health priority as a major cause of child and adolescent morbidity and mortality-over one and a half million children and adolescents develop TB each year. A history of the global public health perspective on child and adolescent TB is followed by 12 narratives detailing challenges and progress in 19 TB endemic low and middle-income countries.

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Data on the management and outcomes of acute myocarditis treated with extracorporeal membrane oxygenation (ECMO) among low- and middle-income countries are limited. This study aimed to determine the short-term outcomes and also identify factors associated with ECMO use among children with acute myocarditis at a tertiary children's hospital in Vietnam. A single-center, retrospective observational study was conducted between January 2016 and February 2021.

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Objectives: Pertussis is an infectious disease that causes epidemics and outbreaks and is associated with a high mortality rate, especially in infants, in both developed and developing countries. We aimed to characterize infants with pertussis with respiratory failure and shock and investigated the factors related to mortality.

Design: A retrospective, observational study conducted between January 2015 and October 2020.

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Introduction: Evidence supporting non-invasive ventilation (NIV) in paediatric acute respiratory distress syndrome (PARDS) remains sparse. We aimed to describe characteristics of patients with PARDS supported with NIV and risk factors for NIV failure.

Materials And Methods: This is a multicentre retrospective study.

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Although the need for palliative care is gaining recognition in Southeast Asia, knowledge about how decisions are made for children near the end of life remains sparse. To explore pediatric intensivists' attitudes and practices surrounding end-of-life care in Vietnam. This is a mixed-methods study conducted at a tertiary pediatric and neonatal intensive care unit in Hanoi.

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Article Synopsis
  • - This study aimed to analyze and compare the characteristics, risk factors for mortality, and outcomes of extrapulmonary versus pulmonary pediatric acute respiratory distress syndrome (ARDS) in mechanically ventilated children across ten PICUs in Asia from 2009 to 2015.
  • - A total of 307 patients were examined, with 41 classified as having extrapulmonary ARDS (primarily caused by sepsis) and 266 with pulmonary ARDS (primarily caused by pneumonia). The extrapulmonary group was found to be older and had more severe health issues at admission.
  • - The primary focus of the analysis was the mortality rate in the Pediatric Intensive Care Unit (PICU), with methods such as Cox proportional hazard regression used to identify
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Objectives: The Pediatric Acute Lung Injury Consensus Conference developed a pediatric specific definition for acute respiratory distress syndrome (PARDS). In this definition, severity of lung disease is stratified into mild, moderate, and severe groups. We aim to describe the epidemiology of patients with PARDS across Asia and evaluate whether the Pediatric Acute Lung Injury Consensus Conference risk stratification accurately predicts outcome in PARDS.

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Article Synopsis
  • A severe outbreak of respiratory infections occurred in two orphanages in Vietnam, resulting in the hospitalization of children and a high mortality rate (7 out of 12 children died).
  • Testing showed that a significant majority (26 out of 43) of children from the affected orphanages were positive for rhinovirus, compared to only 9 out of 40 control children, indicating a strong association with the outbreak (p = 0.0005).
  • The specific rhinoviruses linked to the outbreak formed a unique genetic cluster, highlighting that rhinovirus can be a serious cause of pneumonia, especially in vulnerable populations like orphaned children.
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