and cytotoxic activities of triterpenoids from the leaves of Miq. and the assessment of their ADMET properties.

From the methanol extract of the leaves of Miq. (Araliaceae), ten triterpenoids including five ursane-type triterpenoids, ursolic acid (), 3---l-arabinopyranosyl ursolic acid (), ursolic acid 28---D-glucopyranosyl ester (), 3--[-D-glucopyranosyl (l→3)]--L-arabinopyranosyl ursolic acid (), and matesaponin 1 (), and five oleanane-type triterpenoids, elatoside E (), elatoside F (), 3--[-D-glucopyranosyl (l→3)]-L-arabinopyranosyl oleanolic acid (), 3---L-arabinopyranosyl oleanolic acid () and oleanolic acid 28---D-glucopyranosyl ester () were isolated. Their structures were elucidated based on 1D-, 2D-NMR and ESI-MS spectra as well as by comparison with those reported in the literature.

Polyacetylene and phenolic constituents from the roots of .

Chemical investigation of the roots of resulted in isolation of 12 compounds, including one new polyacetylene, codojavanyol (), one new phenolic glycoside, codobenzyloside (), and 10 known compounds, (2,8)-9-(tetrahydro-2-pyran-2-yl)nona-2,8-diene-4,6-diyl-1-ol (), lobetyol (), lobetyolin (), lobetyolinin (), cordifolioidyne B (), benzyl--L-arabinopyranosyl (1-6)--D-glucopyranoside (), ()-8--D-glucopyranosyloxycinnamic acid (), syringin (), syringaresinol (), and tryptophan (). Their structures were elucidated by 1 D and 2 D NMR and MS spectroscopic analyses in comparison with the data reported in the literature. The stereochemistry of the C-2' position of was identified based on time-dependent density functional theory (TDDFT) electronic circular dichroism (ECD) calculation.

Chemical constituents from the branches and leaves of .

Phytochemical investigation of the branches and leaves of led to isolation of ten secondary metabolites, including two new megastigmane glucosides alnamicosides A () and B (). The structure elucidation was confirmed by 1 D and 2 D NMR, ECD as well as HR-QTOF-MS experiments. The megastigmane derivatives - exhibited inhibitory effects on LPS-induced NO production in RAW264.