Publications by authors named "Pham Quang Duy"
Objectives: We aimed to determine epidemiological characteristics and serologic markers among chronically hepatitis B virus (HBV)-infected pregnant women during the assessment of tenofovir disoproxil fumarate (TDF) prescription in Vietnam.
Methods: We consecutively recruited 375 pregnant women with chronic HBV (cHBV) infection at week 25±2 of pregnancy, at which time they were assessed for TDF use as pre-prophylaxis and/or pre-treatment at the Hospital for Tropical Diseases in southern Vietnam during December 2019-April 2021. Demographic characteristics, serological biomarkers, and prenatal liver ultrasounds were obtained through interviews and reviews of medical records.
Objectives: Our goal was to describe Invasive Meningococcal Disease (IMD) in Southern Vietnam over the last 10 years. We characterized 109 strains in Southern Vietnam isolated between 1980s to 2021, that were collected from IMD (n = 44), sexually transmitted infections (n = 2), and healthy carriage (n = 63).
Methods: IMD were confirmed by bacterial culture and/or real-time polymerase chain reaction at the national reference laboratory in Pasteur Institute of Ho Chi Minh City (PIHCM).
Article Synopsis
- The COVID-19 pandemic increased smart device and internet use among adolescents in Hanoi, leading to a study on internet addiction and anxiety levels in this population.
- Data collected from 5,325 students aged 11-17 showed that around 22.8% faced moderate anxiety and 7.32% faced severe anxiety, with 32.7% showing signs of internet addiction.
- Significant factors linked to higher anxiety included being female, economic hardship in the family, and exposure to domestic violence, emphasizing the need for supportive measures at home and school to promote healthy internet habits.
Chikungunya fever is an acute febrile illness caused by the chikungunya virus (CHIKV), which is transmitted by mosquitoes. Since 1965, only a few studies with limited scope have been conducted on CHIKV in Vietnam. Thus, this study aimed to determine the seroprevalence and molecular epidemiology of CHIKV infection among febrile patients in Vietnam from 2017 to 2019.
View Article and Find Full Text PDFWe report on an outbreak of nongroupable Neisseria meningitidis-associated urethritis, primarily among men who have sex with men in southern Vietnam. Nearly 50% of N. meningitidis isolates were resistant to ciprofloxacin.
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- This study looked at the trends and causes of pneumococcal meningitis in children under 5 in Southern Vietnam after the pentavalent vaccine was introduced in the Expanded Program on Immunization (EPI).
- Over a 10-year period, 2560 suspected cases were reviewed, with only 158 (6.2%) confirmed as bacterial meningitis, mainly caused by a specific pathogen.
- The research found a significant drop in pneumococcal meningitis due to vaccine serotypes, suggesting that policymakers should consider adding pneumococcal conjugate vaccines (PCVs) to immunization programs to better control this disease.
Objective: Female sex workers (FSWs) are at high risk of human papillomavirus (HPV) infections and cervical cancer due to their high number of sexual partners. The objectives of this study were to determine the prevalence of HPV and identify risk factors for high-risk HPV infection among FSWs in Hanoi and Ho Chi Minh City (HCMC), Viet Nam.
Methods: A cross-sectional study was conducted in Hanoi and HCMC between December 2017 and May 2018.
Relatively little is known about the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG antibodies and COVID-19-related behaviors in the general population in Vietnam, where the first case of COVID-19 was detected on January 22, 2020. We surveyed a group of 885 blood donors at community blood donation sessions in Ho Chi Minh City from August 27 to November 7, 2020. Blood was collected to test for SARS-CoV-2 IgG antibodies using the plaque reduction neutralization test.
View Article and Find Full Text PDFBackground/aim: Cervical cancer is the second most common malignancy among women in Vietnam, but the country is yet to introduce a national human papillomavirus (HPV) vaccine programme targeted at adolescents. We determined HPV prevalence and HPV vaccine knowledge among female university students in Vietnam.
Patients And Methods: We surveyed and screened 1,491 female university students in Hanoi, Hue, and Ho Chi Minh City for their sexual behaviours, HPV knowledge and low- and high-risk HPV infection.
Objectives: Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population.
Methods: A cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018.
Background: In 2016-2017, 68 women in Southern Vietnam had RT-PCR confirmed Zika virus (ZIKV) infection during pregnancy. We report here the outcomes of the pregnancies and the virological analyses related to this outbreak.
Methods: We collected clinical and epidemiological information from the women who were enrolled in the study.
Rabies is endemic in Vietnam and has been a statutory notifiable infectious disease since 1998. We, herein, assessed the performance of rabies surveillance in Southern Vietnam and identified areas for improvement. We analyzed data on human rabies cases reported during 1991-2018.
View Article and Find Full Text PDFObjectives: Rotavirus (RV) genotypes vary geographically, and this can affect vaccine effectiveness (VE). This study investigated the genotype distribution of RV and explored VE before introducing the RV vaccine to the national immunization programme in Vietnam.
Methods: This hospital-based surveillance study was conducted at Children's Hospital 1, Ho Chi Minh City in 2013-2018.
We describe the status of the COVID-19 epidemic in Vietnam, major response successes, factors that prompted implementation of certain public health actions, and the impact of these actions. In addition, information for three case studies is reported, with crucial learnings to inform future response. Findings from this study suggest that as early as 20 January 2020, Vietnam held a national risk assessment, established a national COVID-19 Response Plan and Technical Treatment and Care Guidelines, and prepared public health laboratories to accurately diagnose cases and hospitals to effectively treat patients.
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- - The study aimed to estimate the population size of venue-based female sex workers (VFSWs) in Ho Chi Minh City (HCMC), Vietnam, using a multistage capture-recapture method during late 2016 to early 2017.
- - Researchers mapped out 573 venues, distributed a unique object (a pink makeup bag) to 2317 eligible VFSWs, and then conducted a recapture exercise where they interviewed 645 VFSWs across 103 venues to assess how many received the object.
- - The total estimated number of VFSWs in the selected districts was found to be 2616, with a confidence interval of 2445-3014, highlighting the need for accurate population
Mixed neuroendocrine-nonneuroendocrine neoplasm (MiNEN) is defined as mixed epithelial neoplasms composed of both neuroendocrine and nonneuroendocrine components with variable proportions for each component. Neuroendocrine component can show morphological features including well- or poorly differentiated neuroendocrine neoplasms and nonneuroendocrine component can present different tumor types depending on the site of origin. Recently, studies of tumors have shown that MiNENs are not as rare as our traditional belief, due to the wide application for immunohistochemistry.
View Article and Find Full Text PDFLaboratory tests that can distinguish recent from long-term HIV infection are used to estimate HIV incidence in a population, but can potentially misclassify a proportion of long-term HIV infections as recent. Correct application of an assay requires determination of the proportion false recents (PFRs) as part of the assay characterization and for calculating HIV incidence in a local population using a HIV incidence assay. From April 2009 to December 2010, blood specimens were collected from HIV-infected individuals attending nine outpatient clinics (OPCs) in Vietnam (four from northern and five from southern Vietnam).
View Article and Find Full Text PDFObjectives: The objective of this study was to investigate the potential epidemiological impact of viral load (VL) monitoring and its cost-effectiveness in Vietnam, where transmitted HIV drug resistance (TDR) prevalence has increased from <5% to 5%-15% in the past decade.
Methods: Using a population-based mathematical model driven by data from Vietnam, we simulated scenarios of various combinations of VL testing coverage, VL thresholds for second-line ART initiation and availability of HIV drug-resistance tests. We assessed the cost per disability-adjusted life year (DALY) averted for each scenario.
Introduction: Vietnam has been largely reliant on international support in its HIV response. Over 2006-2010, a total of US$480 million was invested in its HIV programmes, more than 70% of which came from international sources. This study investigates the potential epidemiological impacts of these programmes and their cost-effectiveness.
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- - The study aimed to assess the prevalence of pretreatment drug resistance (PDR) to first-line antiretroviral drugs among HIV patients starting treatment in Vietnam, with data collected from 2009 to 2010 across various clinics.
- - Out of 490 participants with detectable viral loads, 3.5% exhibited drug-resistance mutations, with a higher prevalence found in individuals who injected drugs (4.0%) compared to those with sexually acquired HIV (1.4%).
- - The findings suggest that PDR to first-line antiretroviral drugs is low in Vietnam, indicating that first-line treatments are likely effective, though ongoing monitoring and prevention strategies are necessary to maintain this low resistance rate.
Background: Risk behaviors among female sex workers (FSW) are considerable drivers of HIV infections in Vietnam, especially transmission between high-risk and low-risk groups. We assessed HIV prevalence and its correlates among FSWs, and the use of preventive services among this community in the Mekong Delta region, southern Vietnam.
Methods: A cross-sectional survey of 1,999 FSWs was carried out in five provinces including Ben Tre, Hau Giang, Kien Giang, Tien Giang, and Vinh Long between June, 2006 and June, 2007.
Background & Objectives: Little is known about HIV-1 drug resistance (HIVDR) in people failing first-line highly active antiretroviral therapy (HAART) in Vietnam. The aim of this study was to investigate the frequency of HIV-1 drug resistance mutations (DRMs) and determine correlates of acquiring genotypic HIVDR among Vietnamese adults (age ≥ 18) who met the immunological or clinical criteria of first-line HAART failure according to the guidelines of the World Health Organization (WHO).
Methods: A total of 138 individuals participated in a descriptive study in Ho Chi Minh City between 2006 and 2009.
Background: The prevalence of HIV and sexually transmitted infections among men who have sex with men (MSM) has increased substantially in Vietnam. This study aimed to estimate the prevalence of HIV, syphilis, urethral gonorrhoea, and urethral chlamydia, and determined correlates of HIV infection among MSM in An Giang, Vietnam.
Methods: A group of 381 MSM were recruited in a community-based cross-sectional survey between August and December 2009.