Publications by authors named "Phaedra B Hutchison"

Article Synopsis
  • Sanitation guidelines for animal research facilities recommend high-temperature water (143 to 180 °F) for disinfection, but recent studies suggest that lower temperatures may also be effective.
  • In a study comparing cagewash cycles at 100 °F, 120 °F, and 180 °F, it was found that 120 °F effectively sanitized without the need for chemical disinfectants, unlike the 100 °F cycle.
  • Validating effective sanitation at lower temperatures (120 °F) can enhance efficiency and cost-effectiveness in cagewash operations compared to using the higher temperature method.
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Minipig skin is one of the most widely used non-rodent animal skin models for dermatological research. A thorough characterization of minipig skin is essential for gaining deeper understanding of its structural and functional similarities with human skin. In this study, three-dimensional (3-D) images of minipig skin was obtained non-invasively using a multimodal optical imaging system capable of acquiring two-photon excited fluorescence (TPEF) and fluorescence lifetime imaging microscopy (FLIM) images simultaneously.

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