Introduction: The last strategy in targeted drug delivery systems is to deliver the anticancer drug to the tumor tissue to increase its therapeutic effect and minimize its undesirable side effects. In line with this goal in this research, the redox/pH-responsive disulfide magnetic nanocarriers based on PF127-NH2/L-cysteine-CM-β-CD-FA were synthesized and evaluated in a doxorubicin delivery system.
Methods: We effectively surrounded Fe3O4 nanoparticles with SiO2 using the sol-gel method, and then confidently coated them with oleic acid on Fe3O4@SiO2 nanoparticles.
In this work, a polymeric membrane-based polyvinylidene fluoride coated with cellulose and loaded with iron oxide nanoparticles (PVDF/cellulose/FeO) was synthesized and was characterized using FESEM, XRD, AFM, and contact angle measurements. The activity and modification of the PVDF/cellulose/FeO membrane under visible light for the removal of methylene blue were studied using the central composite design. The effect of influential variables such as pH, methylene blue concentration, amount of FeO in the membrane, and irradiation time on MB removal was investigated.
View Article and Find Full Text PDFIn this study, a polymeric adsorbent based on carboxymethyl tragacanth (CMT) grafted by poly acrylic acid-co-acrylamide (AAc-co-AAm) synthesized by radical polymerization for the first time was used to remove the fungicide penconazole (PEN) or Topas 20% from surface water. The parameters of solution pH, adsorption isotherm, and adsorption kinetics of PEN were studied by the synthetic adsorbent. The surface morphology and functional groups of CMT-g-poly (AAc-co-AAm) were confirmed by XRD, SEM and FT-IR techniques.
View Article and Find Full Text PDFIn this research, a new superabsorbent copolymer was synthesized based on the tragacanth gum (TG) via graft polymerization of the acrylic acid onto the carboxymethyl tragacanth (CMT) in the aqueous solution. For this purpose firstly, the carboxymethyl tragacanth was synthesized by reaction of the tragacanth gum and the monochlroroacetic acid in basic conditions. Then the acrylic acid was grafted on the carboxymethyl tragacanth via free radical polymerization.
View Article and Find Full Text PDFIn this study, effective novel magnetic nanocomposite particles (MNCPs) were prepared based on iminodiacetic acid grafted poly (glycidylmethacrylate-maleicanhydride) (PGMA-MAn) copolymer. For this purpose, firstly FeO nanoparticles reacted with 3-aminopropyl triethoxysilane for the production of magnetite nanoparticles containing amine groups (MNPs-NH). Then iminodiacetic acid reacted with PGMA-MAn copolymer to produce iminodiacetic acid grafted PGMA-MAn copolymer (ID-g-PGMA-MAn).
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