Concomitant chest trauma and traumatic brain injury, biomarkers correlate with worse outcomes.

Background: Clinical data are lacking on the influence of chest trauma on the secondary injury process after traumatic brain injury (TBI), with some data suggesting that multiple trauma may worsens brain injury. Blunt chest trauma and TBI represent the two major single injury entities with the highest risk of complications and are potential biomarker targets.

Methods: Trauma patients with severe TBI were enrolled.