With the number of medical school applicants more than doubling during the past 30 years, there has been an increased need to mentor premedical undergraduate students. The Vertically Integrated Training Program at the University of South Carolina School of Medicine, Columbia, was created to provide direct mentoring for college students interested in a career as a physician. Online surveys were distributed at the beginning and end of the Fall 2023 semester to gain insight into the success of the program's events from the undergraduate perspective.
View Article and Find Full Text PDFAgitation in Alzheimer's disease (AAD) is a troubling condition experienced by many of the 6.9 million people living with Alzheimer's disease in the United States. The Gerontological Society of America (GSA) initially published an evidence-based care pathway to treat this condition, Agitation in Alzheimer's Disease: A Decision Tree for Healthcare Providers, in 2022 and updated this resource in 2023 with the International Psychogeriatric Association (IPA) consensus definition of agitation.
View Article and Find Full Text PDFColorectal cancer is the third most common cancer among men and the second among women. In the United States alone, there are 150,000 cases diagnosed each year. Colonoscopy remains the best method for identifying, evaluating, and intervening on patients with precancerous lesions.
View Article and Find Full Text PDFPLoS One
February 2024
The ectoparasitic mite, Varroa destructor is the most serious widespread pest of managed honeybees (Apis mellifera). Several acaricide products, which include essential oils, have been proposed for mite control. In this study, we aimed to apply atmospheric-pressure plasma to modify a cardboard piece surface in order to prolong the delivery of essential oils for controlling Varroa in honeybee colonies.
View Article and Find Full Text PDFAscosphaera apis is a worldwide pathogenic fungi of honeybees that can cause a decline in bee populations. In this study, we investigated the antifungal activity of non-thermal plasma on fungal growth. Spore inactivation after exposure to gas plasma by liquid phase and plasma activated water (PAW) and pathogenicity of A.
View Article and Find Full Text PDFObesity is a chronic and all too often untreated disease that contributes to diabetes, hypertension, liver and kidney disorders, and a variety of other conditions. Additionally, for older adults in particular, obesity can cause functional limitations and decreased independence. In order to support primary care teams to implement a comprehensive and contemporary approach to caring for older adults with obesity, The Gerontological Society of America (GSA) applied its KAER-Kickstart, Assess, Evaluate, Refer-Framework, initially developed as a framework to promote well-being and positive health-related outcomes for people living with dementia and for their families, to caring for older adults with obesity.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) is typically managed with neoadjuvant chemotherapy (NAC). Metaplastic breast cancer (MBC), a subtype of TNBC, demonstrates different histologic characteristics and less responsiveness to NAC. We performed this study to achieve a better understanding of MBC, including the impact of neoadjuvant chemotherapy.
View Article and Find Full Text PDFWidespread parasites, along with emerging threats, globalization, and climate change, have greatly affected honey bees' health, leading to colony losses worldwide. In this study, we investigated the detection of biotic stressors (i.e.
View Article and Find Full Text PDFNosema disease is one factor that can cause colony decline in honeybees (Apis mellifera L.) worldwide. Nosema ceranae has outcompeted Nosema apis in the Western honeybee (A.
View Article and Find Full Text PDFHoney bee colony losses worldwide call for a more in-depth understanding of the pathogenic and mutualistic components of the honey bee microbiota and their relation with the environment. In this descriptive study, we characterized the yeast and bacterial communities that arise from six substrates associated with honey bees: corbicular pollen, beebread, hive debris, intestinal contents, body surface of nurses and forager bees, comparing two different landscapes, Minas Gerais, Brazil and Maryland, United States. The sampling of five hives in Brazil and four in the USA yielded 217 yeast and 284 bacterial isolates.
View Article and Find Full Text PDFHoney bees Apis mellifera forage in a wide radius around their colony, bringing back contaminated food resources that can function as terrestrial bioindicators of environmental pesticide exposure. Evaluating pesticide exposure risk to pollinators is an ongoing problem. Here we apply five metrics for pesticide exposure risk (prevalence, diversity, concentration, significant pesticide prevalence, and hazard quotient (HQ)) to a nation-wide field study of honey bees, Apis mellifera in the United States.
View Article and Find Full Text PDFBeekeepers struggle to minimize the mortality of their colonies as a consequence of the parasitic mite Varroa destructor in order to maintain a sustainable managed pollinator population. However, little is known about how varroa mites might diminish local populations of honey bee males (drones) that might affect the mating success of queens. As one of the world's last localities invaded by varroa mites, the Hawaiian Islands offer a unique opportunity to examine this question by comparing queens mated on mite-infested and mite-free islands.
View Article and Find Full Text PDFQueens of many social hymenoptera keep sperm alive within their specialized storage organ, the spermatheca, for years, defying the typical trade-off between lifespan and reproduction. However, whether honey bee (Apis mellifera) queens experience a trade-off between reproduction and immunity is unknown, and the biochemical processes underlying sperm viability are poorly understood. Here, we survey quality metrics and viral loads of honey bee queens from nine genetic sources.
View Article and Find Full Text PDFMentorship is vital in the effective progression of a physician's educational training. This journey often begins during a physician's undergraduate career prior to advancing on to medical school, residency, and fellowship training. These levels of training distinguish different tiers of mastery, and collaboration among these tiers is integral in order to facilitate a meaningful transition into an independent physician.
View Article and Find Full Text PDFBackground: Queen failure is a persistent problem in beekeeping operations, but in the absence of overt symptoms it is often difficult, if not impossible, to ascertain the root cause. Stressors like heat-shock, cold-shock, and sublethal pesticide exposure can reduce stored sperm viability and lead to cryptic queen failure. Previously, we suggested candidate protein markers indicating heat-shock in queens.
View Article and Find Full Text PDFIn this study, we examined the impact of Sacbrood virus (SBV), the cause of larval honeybee () death, producing a liquefied a larva sac, on the gut bacterial communities on two larval honeybee species, and . SBV was added into a worker jelly food mixture and bee larvae were grafted into each of the treatment groups for 24 h before DNA/RNA extraction. Confirmation of SBV infection was achieved using quantitative reverse transcription polymerase chain reaction (RT-qPCR) and visual symptomology.
View Article and Find Full Text PDFThe older adult population is growing in number and diversity, and this population has unique care needs that the current healthcare system is ill prepared to meet. In order to ensure older adults receive safe, person-centered care that supports their goals, the John A. Hartford Foundation has developed and, with their partners at the Institute for Healthcare Improvement, the American Hospital Association, and Catholic Health Association of the United States, is implementing across the United States the Age-Friendly Health Systems Initiative.
View Article and Find Full Text PDFHoney bees are experts at refuting societal norms. Their matriarchal hives are headed by queens, backed by an all-female workforce, and males die soon after copulation. But the biochemical basis of how these distinct castes and sexes (queens, workers, and drones) arise is poorly understood, partly due to a lack of efficient tools for genetic manipulation.
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